Phytoconstituents Targeting the Serotonin 5-HT3 Receptor: Promising Therapeutic Strategies for Neurological Disorders

L Akotkar, U Aswar, A Ganeshpurkar… - ACS Pharmacology & …, 2024 - ACS Publications
The 5-hydroxytryptamine-3 receptor (5-HT3R), a subtype of serotonin receptor, is a ligand-
gated ion channel crucial in mediating fast synaptic transmission in the central and …

Pterostilbene alleviates cafeteria diet-induced obesity and underlying depression in adolescent male Swiss albino mice and affects insulin resistance, inflammation …

R Patil, U Aswar, N Vyas - Hormones and Behavior, 2024 - Elsevier
Cafeteria diet (CD) model for in-vivo studies mimics the western diet having imbalanced
nutritional value, high caloric-density and palatability. Uncontrolled eating leads to the …

Resveratrol attenuates early life stress induced depression in rats: Behavioural and neurochemical evidence

P Shukla, L Akotkar, U Aswar - Neuroscience Letters, 2024 - Elsevier
Purpose Maternal deprivation (MD), a severe naturalistic type of stress in the early postnatal
days, is a well-established model of early life stress (ELS) that models juvenile adversity and …