Associations of the cardiometabolic index with the risk of cardiovascular disease in patients with hypertension and obstructive sleep apnea: results of a longitudinal …

X Cai, J Hu, W Wen, J Wang, M Wang… - Oxidative Medicine …, 2022 - Wiley Online Library
Purpose. We aimed to explore the relationship between the cardiometabolic index (CMI)
and cardiovascular disease (CVD) and its subtypes (coronary artery disease and stroke) in …

Reflections on the state of diabetes research and prospects for treatment

D Accili, W Du, T Kitamoto, T Kuo, W McKimpson… - Diabetology …, 2023 - Springer
Research on the etiology and treatment of diabetes has made substantial progress. As a
result, several new classes of anti-diabetic drugs have been introduced in clinical practice …

BMI, insulin sensitivity, and cognition in early type 2 diabetes: The Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study

JA Luchsinger, EJ Kazemi, DL Sanchez, ME Larkin… - …, 2023 - Wiley Online Library
Objective This study explored the association of BMI and insulin sensitivity with cognitive
performance in type 2 diabetes. Methods A cross‐sectional analysis of data from the …

Longitudinal Effects of Glucose-Lowering Medications on β-Cell Responses and Insulin Sensitivity in Type 2 Diabetes: The GRADE Randomized Clinical Trial

N Rasouli, N Younes, A Ghosh, J Albu… - Diabetes …, 2024 - Am Diabetes Assoc
OBJECTIVE To compare the long-term effects of glucose-lowering medications (insulin
glargine U-100, glimepiride, liraglutide, sitagliptin) when added to metformin on insulin …

Critical Evaluation of Indices Used to Assess β-Cell Function

C Cao, HCE Koh, DN Reeds, BW Patterson, S Klein… - Diabetes, 2024 - Am Diabetes Assoc
The assessment of β-cell function, defined as the relationship between insulin secretion rate
(ISR) and plasma glucose, is not standardized and often involves any of a number of β-cell …

Pseudotime Ordering Single-Cell Transcriptomic of β Cells Pancreatic Islets in Health and Type 2 Diabetes

K Bao, Z Cui, H Wang, H Xiao, T Li, X Kong, T Liu - Phenomics, 2021 - Springer
Abstract β cells are defined by the ability to produce and secret insulin. Recent studies have
evaluated that human pancreatic β cells are heterogeneous and demonstrated the transcript …

Racial differences in measures of glycemia in the Vitamin D and Type 2 Diabetes (D2d) Study: a secondary analysis of a randomized trial

ES LeBlanc, AG Pittas, J Nelson… - BMJ Open Diabetes …, 2024 - drc.bmj.com
Introduction Understanding how race may influence the association between A1c and
glycemia can improve diabetes screening. We sought to determine whether, for a given A1c …

[HTML][HTML] Glycemic and metabolic sub-classification of prediabetes and risk factors for cardiovascular disease in the D2d cohort

SR Kashyap, C Desouza, VR Aroda, SH Kim… - American Journal of …, 2023 - Elsevier
Objectives Prediabetes represents a spectrum of metabolic abnormalities, including insulin
resistance and secretory impairment, that carries increased cardiovascular disease (CVD) …

Interaction between the GCKR rs1260326 variant and serum HDL cholesterol contributes to HOMA-β and ISIMatusda in the middle-aged T2D individuals

M Shen, L Jiang, H Liu, H Dai, H Jiang, Y Qian… - Journal of Human …, 2023 - nature.com
This study aims to investigate the correlations between islet function/insulin resistance and
serum lipid levels, as well as to assess whether the strength of such correlations is affected …

Differences in complications, cardiovascular risk factor, and diabetes management among participants enrolled at veterans affairs (VA) and non-VA medical centers in …

HJ Florez, A Ghosh, R Pop-Busui, SH Hox… - Diabetes research and …, 2022 - Elsevier
Aims We evaluated differences in participants with type 2 diabetes (T2DM) enrolled in the
GRADE study at VA vs non-VA sites, focusing on cardiovascular risk factors and rates of …