[HTML][HTML] Obesity hypoventilation syndrome

JF Masa, JL Pépin, JC Borel, B Mokhlesi… - European …, 2019 - Eur Respiratory Soc
Obesity hypoventilation syndrome (OHS) is defined as a combination of obesity (body mass
index≥ 30 kg· m− 2), daytime hypercapnia (arterial carbon dioxide tension≥ 45 mmHg) and …

Precision medicine in obstructive sleep apnoea

MA Martinez-Garcia, F Campos-Rodriguez… - The Lancet …, 2019 - thelancet.com
Obstructive sleep apnoea (OSA) is a heterogeneous and complex disease; however,
diagnosis and management still rely on a simple set of tools and few therapeutic options …

Evaluation and management of obesity hypoventilation syndrome. An official American Thoracic Society clinical practice guideline

B Mokhlesi, JF Masa, JL Brozek… - American journal of …, 2019 - atsjournals.org
Background: The purpose of this guideline is to optimize evaluation and management of
patients with obesity hypoventilation syndrome (OHS). Methods: A multidisciplinary panel …

Non-invasive ventilation in obesity hypoventilation syndrome without severe obstructive sleep apnoea

JF Masa, J Corral, C Caballero, E Barrot… - Thorax, 2016 - thorax.bmj.com
Background Non-invasive ventilation (NIV) is an effective form of treatment in patients with
obesity hypoventilation syndrome (OHS) who have concomitant severe obstructive sleep …

Hypoxia induces de novo formation of cerebral collaterals and lessens the severity of ischemic stroke

H Zhang, W Rzechorzek… - Journal of Cerebral …, 2020 - journals.sagepub.com
Pial collaterals provide protection in stroke. Evidence suggests their formation late during
gestation (collaterogenesis) is driven by reduced oxygen levels in the cerebral watersheds …

[HTML][HTML] Long-term noninvasive ventilation in obesity hypoventilation syndrome without severe OSA: the Pickwick randomized controlled trial

JF Masa, I Benítez, MÁ Sánchez-Quiroga… - Chest, 2020 - Elsevier
Background Noninvasive ventilation (NIV) is an effective form of treatment in obesity
hypoventilation syndrome (OHS) with severe OSA. However, there is paucity of evidence in …

Echocardiographic changes with positive airway pressure therapy in obesity hypoventilation syndrome. Long-term Pickwick randomized controlled clinical trial

JF Masa, B Mokhlesi, I Benítez… - American Journal of …, 2020 - atsjournals.org
Rationale: Obesity hypoventilation syndrome (OHS) has been associated with cardiac
dysfunction. However, randomized trials assessing the impact of long-term noninvasive …

The association between sleep breathing impairment index and cardiovascular risk in male patients with obstructive sleep apnea

W Cao, J Luo, R Huang, Y Xiao - Nature and Science of Sleep, 2022 - Taylor & Francis
Background Obstructive sleep apnea (OSA) is related to multiple complications including
insulin resistance (IR), endothelial dysfunction, and increased risk of cardiovascular disease …

The impact of obstructive sleep apnea and PAP therapy on all-cause and cardiovascular mortality based on age and gender–a literature review

S Mashaqi, D Gozal - Respiratory investigation, 2020 - Elsevier
Background Obstructive sleep apnea (OSA) is a common sleep disorder which negatively
impacts different body systems, especially the cardiovascular system. The correlation …

Sleep-disordered breathing, circulating exosomes, and insulin sensitivity in adipocytes

A Khalyfa, D Gozal, JF Masa, JM Marin… - International Journal of …, 2018 - nature.com
Abstract Background: Sleep-disordered-breathing (SDB), which is characterized by chronic
intermittent hypoxia (IH) and sleep fragmentation (SF), is a prevalent condition that promotes …