Multicomponent reactions are flexible reactions for the rapid generation of complex
molecules with often biologically relevant scaffold structures. Combined with the ease of …

Dihydropyrimidinones are heterocycles with a pyrimidine moiety in the ring nucleus, which,
in recent decades, have aroused interest in medicinal chemistry due to alleged versatile …

This review covers up to 2010 and some available references of 2011 of synthetic advances
in the Biginelli reaction, including recent mechanistic advances, new building blocks, new …

The present work describes the synthesis, characterization, and application of a new ion‐
tagged iron catalyst. The catalyst was employed in the Biginelli reaction with impressive …

A microwave-assisted, copper-catalyzed three-component synthesis of dihydropyrimidinones
under mild conditions - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals …

The Biginelli Reaction is a one-pot acid catalysed cyclocondensation of β-keto ester, urea
and aromatic aldehyde which leads to the synthesis of functionalised 3, 4-dihydro-2 (H) …

The interest in 3, 4-dihydropyrimidine-2 (1 H)-(thio) ones is increasing every day, mainly due
to their paramount biological relevance. The Biginelli reaction is the classical approach to …

The synthesis of dihydropyrimidinones and dihydropyrimidine thiones has attracted interest
due to their biological activities. A common method for their synthesis is the Biginelli …

We described the first synthesis of fatty acid 3, 4-dihydropyrimidinones (DHPM-fatty acids)
using the Biginelli multicomponent reaction. Antiproliferative activity on two glioma cell lines …

A series of Biginelli adducts bearing different substituents at C-4 position were synthesized
by using p-sulfonic acid calix [4] arene as a catalyst. The in vitro potential to scavenge …