[HTML][HTML] Ebola virus disease

ST Jacob, I Crozier, WA Fischer, A Hewlett… - Nature reviews Disease …, 2020 - nature.com
Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …

The pathogenesis of Ebola virus disease

L Baseler, DS Chertow, KM Johnson… - Annual Review of …, 2017 - annualreviews.org
For almost 50 years, ebolaviruses and related filoviruses have been repeatedly reemerging
across the vast equatorial belt of the African continent to cause epidemics of highly fatal …

Exuberant elevation of IP-10, MCP-3 and IL-1ra during SARS-CoV-2 infection is associated with disease severity and fatal outcome

Y Yang, C Shen, J Li, J Yuan, M Yang, F Wang, G Li… - MedRxiv, 2020 - medrxiv.org
The outbreak of Coronavirus Disease 2019 (COVID-19) caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, December 2019 …

A randomized, controlled trial of ZMapp for Ebola virus infection

Prevail II Writing Group - New England Journal of Medicine, 2016 - Mass Medical Soc
Background Data from studies in nonhuman primates suggest that the triple monoclonal
antibody cocktail ZMapp is a promising immune-based treatment for Ebola virus disease …

Ebola virus disease

D Malvy, AK McElroy, H de Clerck, S Günther… - The Lancet, 2019 - thelancet.com
Ebolaviruses are pathogenic agents associated with a severe, potentially fatal, systemic
disease in man and great apes. Four species of ebolaviruses have been identified in west or …

Diagnosis of Ebola virus disease: past, present, and future

MJ Broadhurst, TJG Brooks… - Clinical microbiology …, 2016 - Am Soc Microbiol
Laboratory diagnosis of Ebola virus disease plays a critical role in outbreak response efforts;
however, establishing safe and expeditious testing strategies for this high-biosafety-level …

[HTML][HTML] Ebola virus glycoprotein with increased infectivity dominated the 2013–2016 epidemic

WE Diehl, AE Lin, ND Grubaugh, LM Carvalho, K Kim… - Cell, 2016 - cell.com
The magnitude of the 2013–2016 Ebola virus disease (EVD) epidemic enabled an
unprecedented number of viral mutations to occur over successive human-to-human …

[HTML][HTML] Ebola virus disease: An emerging and re-emerging viral threat

M Rojas, DM Monsalve, Y Pacheco… - Journal of …, 2020 - Elsevier
The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …

Ebola virus shedding and transmission: review of current evidence

P Vetter, WA Fischer, M Schibler… - The Journal of …, 2016 - academic.oup.com
Background. The magnitude of the 2013–2016 Ebola virus disease outbreak in West Africa
was unprecedented, with> 28 500 reported cases and> 11 000 deaths. Understanding the …

[HTML][HTML] Unique human immune signature of Ebola virus disease in Guinea

P Ruibal, L Oestereich, A Lüdtke, B Becker-Ziaja… - Nature, 2016 - nature.com
Despite the magnitude of the Ebola virus disease (EVD) outbreak in West Africa, there is still
a fundamental lack of knowledge about the pathophysiology of EVD. In particular, very little …