Neurons in the suprachiasmatic nucleus (SCN) function as part of a central timing circuit that
drives daily changes in our behaviour and underlying physiology. A hallmark feature of SCN …

The biological clocks of the circadian timing system coordinate cellular and physiological
processes and synchronizes these with daily cycles, feeding patterns also regulates …

Compelling reasons to study the role of sex in the circadian system include the higher rates
of sleep disorders in women than in men and evidence that sex steroids modulate circadian …

Brain plasticity, the ability of the nervous system to encode experience, is a modulatory
process leading to long-lasting structural and functional changes. Salient experiences …

The circadian clock regulates bodily rhythms by time cues that result from the integration of
genetically encoded endogenous rhythms with external cycles, most potently with the …

Robust physiological circadian rhythms form an integral part of well-being. The aging
process has been found to negatively impact systems that drive circadian physiology …

The neuropeptide vasoactive intestinal peptide (VIP) is expressed at high levels in a subset
of neurons in the ventral region of the suprachiasmatic nucleus (SCN). While VIP is known to …

NMDA receptors play dual and opposing roles in neuronal survival by mediating the activity‐
dependent neurotrophic signaling and excitotoxic cell death via synaptic and extrasynaptic …

Uncaria rhynchophylla is a plant highly used in the traditional Chinese and Japanese
medicines. It has numerous health benefits, which are often attributed to its alkaloid …

The chondrocyte circadian clock is altered in osteoarthritis. This change is implicated in the
disease-associated changes in chondrocyte phenotype and cartilage loss. Why the clock is …