Capillary forces generated by biomolecular condensates
Liquid–liquid phase separation and related phase transitions have emerged as generic
mechanisms in living cells for the formation of membraneless compartments or biomolecular …
mechanisms in living cells for the formation of membraneless compartments or biomolecular …
Physical principles underlying the complex biology of intracellular phase transitions
JM Choi, AS Holehouse… - Annual review of …, 2020 - annualreviews.org
Many biomolecular condensates appear to form via spontaneous or driven processes that
have the hallmarks of intracellular phase transitions. This suggests that a common …
have the hallmarks of intracellular phase transitions. This suggests that a common …
Liquid phase condensation in cell physiology and disease
Y Shin, CP Brangwynne - Science, 2017 - science.org
BACKGROUND Living cells contain distinct subcompartments to facilitate spatiotemporal
regulation of biological reactions. In addition to canonical membrane-bound organelles such …
regulation of biological reactions. In addition to canonical membrane-bound organelles such …
Screening membraneless organelle participants with machine-learning models that integrate multimodal features
Protein self-assembly is one of the formation mechanisms of biomolecular condensates.
However, most phase-separating systems (PS) demand multiple partners in biological …
However, most phase-separating systems (PS) demand multiple partners in biological …
Liquid-liquid phase separation in biology: mechanisms, physiological functions and human diseases
Cells are compartmentalized by numerous membrane-enclosed organelles and
membraneless compartments to ensure that a wide variety of cellular activities occur in a …
membraneless compartments to ensure that a wide variety of cellular activities occur in a …
Autonomous materials systems from active liquid crystals
Liquid crystals (LCs) are ubiquitous in display technologies. The orientational ordering in the
nematic phase of LCs gives rise to structural anisotropy, the ability to form topological …
nematic phase of LCs gives rise to structural anisotropy, the ability to form topological …
Supramolecular polymers form tactoids through liquid–liquid phase separation
H Fu, J Huang, JJB van der Tol, L Su, Y Wang, S Dey… - Nature, 2024 - nature.com
Liquid–liquid phase separation (LLPS) of biopolymers has recently been shown to play a
central role in the formation of membraneless organelles with a multitude of biological …
central role in the formation of membraneless organelles with a multitude of biological …
Mechanisms for active regulation of biomolecular condensates
Liquid–liquid phase separation is a key organizational principle in eukaryotic cells, on par
with intracellular membranes. It allows cells to concentrate specific proteins into …
with intracellular membranes. It allows cells to concentrate specific proteins into …
The actin cytoskeleton as an active adaptive material
S Banerjee, ML Gardel… - Annual review of …, 2020 - annualreviews.org
Actin is the main protein used by biological cells to adapt their structure and mechanics to
their needs. Cellular adaptation is made possible by molecular processes that strongly …
their needs. Cellular adaptation is made possible by molecular processes that strongly …