Recent advances bioactive 1, 2, 4-triazole-3-thiones
ŞG Küçükgüzel, P Çıkla-Süzgün - European journal of medicinal chemistry, 2015 - Elsevier
Triazoles are heterocyclic compounds which have a five-membered ring of two carbon
atoms and three nitrogen atoms. These structures have been interest in the development of …
atoms and three nitrogen atoms. These structures have been interest in the development of …
Thiadiazole—A promising structure in medicinal chemistry
Y Li, J Geng, Y Liu, S Yu, G Zhao - ChemMedChem, 2013 - Wiley Online Library
Many compounds containing a five‐membered heterocyclic ring display exceptional
chemical properties and versatile biological activities. In this Minireview, thiadiazoles are …
chemical properties and versatile biological activities. In this Minireview, thiadiazoles are …
Synthesis, biological assay in vitro and molecular docking studies of new Schiff base derivatives as potential urease inhibitors
A series of new and novel Schiff base derivatives were synthesized and investigated as
potential new inhibitors of Jack bean urease. The most potent compounds were 3f with (Ki …
potential new inhibitors of Jack bean urease. The most potent compounds were 3f with (Ki …
Urease inhibitors as potential drugs for gastric and urinary tract infections: a patent review
P Kosikowska, Ł Berlicki - Expert opinion on therapeutic patents, 2011 - Taylor & Francis
Introduction: Urease is the enzyme that catalyzes the hydrolysis of urea, which is involved in
serious infections caused by Helicobacter pylori in the gastric tract, as well as Proteus and …
serious infections caused by Helicobacter pylori in the gastric tract, as well as Proteus and …
[HTML][HTML] Anti-Helicobacter pylori and Urease Inhibition Activities of Some Traditional Medicinal Plants
Different parts of Acacia nilotica (L.) Delile, Calotropis procera (Aiton) WT Aiton, Adhatoda
vasica Nees, Fagoniaar abica L. and Casuarina equisetifolia L. are traditionally used in folk …
vasica Nees, Fagoniaar abica L. and Casuarina equisetifolia L. are traditionally used in folk …
Structural biology and drug discovery
G Scapin - Current pharmaceutical design, 2006 - ingentaconnect.com
In the past few years macromolecular crystallography has become a standard technique
used by many pharmaceutical and biotechnology companies. This methodology offers …
used by many pharmaceutical and biotechnology companies. This methodology offers …
[HTML][HTML] Expression, Purification, and Comparative Inhibition of Helicobacter pylori Urease by Regio-Selectively Alkylated Benzimidazole 2-Thione Derivatives
The urease enzyme has been an important target for the discovery of effective
pharmacological and agricultural products. Thirteen regio-selectively alkylated …
pharmacological and agricultural products. Thirteen regio-selectively alkylated …
Syntheses, in vitro α-amylase and α-glucosidase dual inhibitory activities of 4-amino-1, 2, 4-triazole derivatives their molecular docking and kinetic studies
Abstract Thirty-three 4-amino-1, 2, 4-triazole derivatives 1–33 were synthesized by reacting
4-amino-1, 2, 4-triazole with a variety of benzaldehydes. The synthetic molecules were …
4-amino-1, 2, 4-triazole with a variety of benzaldehydes. The synthetic molecules were …
[HTML][HTML] The combined influences of exercise, diet and sleep on neuroplasticity
JW Pickersgill, CV Turco, K Ramdeo, RS Rehsi… - Frontiers in …, 2022 - frontiersin.org
Neuroplasticity refers to the brain's ability to undergo structural and functional adaptations in
response to experience, and this process is associated with learning, memory and …
response to experience, and this process is associated with learning, memory and …
[HTML][HTML] Green synthesis and characterization of silver nanoparticles through the Piper cubeba ethanolic extract and their enzyme inhibitory activities
The area of'Green Synthesis of Nano-medicine'as compared to synthetic counterparts is
relatively a safer research technology for various biomedical applications, including …
relatively a safer research technology for various biomedical applications, including …