[HTML][HTML] Tumor necrosis factor receptors: pleiotropic signaling complexes and their differential effects
P Gough, IA Myles - Frontiers in immunology, 2020 - frontiersin.org
Since its discovery in 1975, TNFα has been a subject of intense study as it plays significant
roles in both immunity and cancer. Such attention is well deserved as TNFα is unique in its …
roles in both immunity and cancer. Such attention is well deserved as TNFα is unique in its …
TNF production and release from microglia via extracellular vesicles: impact on brain functions
S Raffaele, M Lombardi, C Verderio, M Fumagalli - Cells, 2020 - mdpi.com
Tumor necrosis factor (TNF) is a pleiotropic cytokine powerfully influencing diverse
processes of the central nervous system (CNS) under both physiological and pathological …
processes of the central nervous system (CNS) under both physiological and pathological …
[HTML][HTML] CRISPR/Cas9-engineered mesenchymal stromal/stem cells and their extracellular vesicles: A new approach to overcoming cell therapy limitations
Cell therapy is one of the newest therapeutic approaches for treating tissue destruction
diseases and replacing damaged parts in defective tissues. Among different cells …
diseases and replacing damaged parts in defective tissues. Among different cells …
Exposure to ambient dusty particulate matter impairs spatial memory and hippocampal LTP by increasing brain inflammation and oxidative stress in rats
Objectives Exposure of healthy subjects to ambient airborne dusty particulate matter (PM)
causes brain dysfunction. This study aimed to investigate the effect of sub-chronic inhalation …
causes brain dysfunction. This study aimed to investigate the effect of sub-chronic inhalation …
[HTML][HTML] Anti-aging effects of Ribes meyeri anthocyanins on neural stem cells and aging mice
J Gao, Y Wu, D He, X Zhu, H Li, H Liu, H Liu - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Aging is associated with neurological impairment and cognitive decline. Flavonoids are very
promising in anti-aging research in mouse models. Ribes meyeri anthocyanins are rich in …
promising in anti-aging research in mouse models. Ribes meyeri anthocyanins are rich in …
[HTML][HTML] Peripheral blood leukocyte RNA-Seq identifies a set of genes related to abnormal psychomotor behavior characteristics in patients with schizophrenia
Y Zhang, X You, S Li, Q Long, Y Zhu… - … medical journal of …, 2020 - ncbi.nlm.nih.gov
Background Schizophrenia is a multigene disease with a complex etiology and different
clinical manifestations. It is of great significance to understand the etiology and …
clinical manifestations. It is of great significance to understand the etiology and …
[HTML][HTML] Effects of aging on the motor, cognitive and affective behaviors, neuroimmune responses and hippocampal gene expression
The known effects of aging on the brain and behavior include impaired cognition, increases
in anxiety and depressive-like behaviors, and reduced locomotor activity. Environmental …
in anxiety and depressive-like behaviors, and reduced locomotor activity. Environmental …
Effects of Gallic Acid on Memory Deficits and Electrophysiological Impairments Induced by Cerebral Ischemia/Reperfusion in Rats Following Exposure to Ambient …
We aimed to investigate the probable protective effects of gallic acid (GA) on cognitive
deficits, hippocampal long term potentiation (LTP) impairments, and molecular changes …
deficits, hippocampal long term potentiation (LTP) impairments, and molecular changes …
Integrated phytochemical analysis based on UHPLC-LTQ–Orbitrap and network pharmacology approaches to explore the potential mechanism of Lycium ruthenicum …
Z Luo, G Yu, X Chen, Y Liu, Y Zhou, G Wang, Y Shi - Food & function, 2020 - pubs.rsc.org
Based on compelling experimental and clinical evidence, the fruit of Lycium ruthenicum
Murr.(LRM), a unique traditional Tibetan medicine, exerts beneficial effects on ameliorating …
Murr.(LRM), a unique traditional Tibetan medicine, exerts beneficial effects on ameliorating …
[HTML][HTML] Brain aging and electrophysiological signaling: revisiting the spreading depression model
RCA Guedes, R Abadie-Guedes - Frontiers in Aging Neuroscience, 2019 - frontiersin.org
As a consequence of worldwide improvement in health care, the aging portion of the human
population has increased, now representing a higher proportion of the total population. This …
population has increased, now representing a higher proportion of the total population. This …