The formation of adipocytes during embryogenesis has been largely understudied.
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem …

The blood-brain barrier (BBB) is composed of tightly bound endothelial cells (ECs) and
perivascular astrocytes that regulate central nervous system (CNS) homeostasis. We …

Loss of alveolar type 2 cells (AEC2s) and the ectopic appearance of basal cells in the alveoli
characterize severe lung injuries such as idiopathic pulmonary fibrosis (IPF). Here we …

Bioprinting promises enormous control over the spatial deposition of cells in three
dimensions,,,,,–, but current approaches have had limited success at reproducing the …

INTRODUCTION The association between tumors and inflammation is a long-established
clinical observation. Although many studies have demonstrated that the inflammatory …

Metastasis is the major driver of death in patients with cancer. Invasion of surrounding
tissues and metastasis have been proposed to initiate following loss of the intercellular …

Triple-negative breast cancer (TNBC) is an aggressive subtype associated with early
metastatic recurrence and worse patient outcomes. TNBC tumors express molecular …

Background: Rupture and erosion of advanced atherosclerotic lesions with a resultant
myocardial infarction or stroke are the leading worldwide cause of death. However, we have …

Stromal cells in adult bone marrow that express leptin receptor (LEPR) are a critical source
of growth factors, including stem cell factor (SCF), for the maintenance of haematopoietic …

Although single-cell RNA sequencing studies have begun to provide compendia of cell
expression profiles,,,,,,,–, it has been difficult to systematically identify and localize all …