Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Basic principles and recent advances in magnetic cell separation

M Frenea-Robin, J Marchalot - Magnetochemistry, 2022 - mdpi.com
Magnetic cell separation has become a key methodology for the isolation of target cell
populations from biological suspensions, covering a wide spectrum of applications from …

The proteomic analysis of breast cell line exosomes reveals disease patterns and potential biomarkers

Y Risha, Z Minic, SM Ghobadloo, MV Berezovski - Scientific reports, 2020 - nature.com
Cancer cells release small extracellular vesicles, exosomes, that have been shown to
contribute to various aspects of cancer development and progression. Differential analysis of …

[HTML][HTML] Circulating tumor cell clusters: What we know and what we expect

Y Hong, F Fang, Q Zhang - … journal of oncology, 2016 - spandidos-publications.com
The major cause of cancer-associated mortality is tumor metastasis, a disease that is far
from understood. Many studies have observed circulating tumor cells (CTCs) in patients' …

Current and prospective protein biomarkers of lung cancer

TN Zamay, GS Zamay, OS Kolovskaya, RA Zukov… - Cancers, 2017 - mdpi.com
Lung cancer is a malignant lung tumor with various histological variants that arise from
different cell types, such as bronchial epithelium, bronchioles, alveoli, or bronchial mucous …

The application of Aptamer in biomarker discovery

Y Li, WW Tam, Y Yu, Z Zhuo, Z Xue, C Tsang, X Qiao… - Biomarker …, 2023 - Springer
Biomarkers are detectable molecules that can reflect specific physiological states of cells,
organs, and organisms and therefore be regarded as indicators for specific diseases. And …

[HTML][HTML] Clinical and biological significance of circulating tumor cells in cancer

T Masuda, N Hayashi, T Iguchi, S Ito, H Eguchi… - Molecular …, 2016 - Elsevier
During the process of metastasis, which is the leading cause of cancer-related death, cancer
cells dissociate from primary tumors, migrate to distal sites, and finally colonize, eventually …

Electrochemical aptasensors for cancer diagnosis in biological fluids–a review

A Díaz-Fernández, R Lorenzo-Gómez… - Analytica Chimica …, 2020 - Elsevier
The tunability of SELEX procedure is an essential feature to supply bioaffinity receptors
(aptamers) almost on demand for analytical and therapeutic purposes. This longstanding …

Optical and electrochemical-based nano-aptasensing approaches for the detection of circulating tumor cells (CTCs)

H Safarpour, S Dehghani, R Nosrati… - Biosensors and …, 2020 - Elsevier
More recently, detection of circulating tumor cells (CTCs) has been considered as an
appealing prognostic and diagnostic approach for cancer patients. CTCs as a type of tumor …

State-of-the-art nanotechnologies for the detection, recovery, analysis and elimination of liquid biopsy components in cancer

M Zhao, D Mi, BE Ferdows, Y Li, R Wang, J Li, D Patel… - Nano Today, 2022 - Elsevier
Liquid biopsy allows for the quick and noninvasive detection of tumor-associated
components. Various liquid biopsy components, which include circulating tumor cells, tumor …