Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …

During the past decade, the number of studies describing nanostructured lipid carriers
(NLCs)-based formulations has been dramatically increased. The raise in NLC exploitation …

In the last decade, biological drugs have rapidly proliferated and have now become an
important therapeutic modality. This is because of their high potency, high specificity and …

Highlights•Clearance routes of nanoparticles in the lung are presented.•Factors influencing
nanoparticle transaction are discussed.•Physicochemical properties of the nanoparticles …

Pulmonary administration route has been extensively exploited for the treatment of local
lung diseases such as asthma, chronic obstructive pulmonary diseases and respiratory …

Drug delivery to the lungs by inhalation offers a targeted drug therapy for respiratory
diseases. However, the therapeutic efficacy of inhaled drugs is limited by their rapid …

In the last three decades, polymers have contributed significantly to the improvement of drug
delivery technologies by enabling the controlled and sustained release of therapeutic …

Neurodegenerative diseases have an increased prevalence and incidence nowadays,
mainly due to aging of the population. In addition, current treatments lack efficacy, mostly …

With excellent physicochemical properties, inorganic nanomaterials (INMs) have exhibited a
series of attractive applications in biomedical fields. Biological barriers prevent successful …

Ever since the success of developing inhalable insulin, drug delivery via pulmonary
administration has become an attractive route to treat chronic diseases. Pulmonary delivery …