The hitchhiker's guide to flow chemistry∥

MB Plutschack, B Pieber, K Gilmore… - Chemical …, 2017 - ACS Publications
Flow chemistry involves the use of channels or tubing to conduct a reaction in a continuous
stream rather than in a flask. Flow equipment provides chemists with unique control over …

Process intensification

FJ Keil - Reviews in Chemical Engineering, 2018 - degruyter.com
Process intensification (PI) is a rapidly growing field of research and industrial development
that has already created many innovations in chemical process industry. PI is directed …

Flow chemistry—microreaction technology comes of age

KF Jensen - AIChE Journal, 2017 - Wiley Online Library
Over the past two decades, microreaction technology has matured from early devices and
concepts to encompass a wide range of commercial equipment and applications. This …

Advanced real‐time process analytics for multistep synthesis in continuous flow

P Sagmeister, R Lebl, I Castillo, J Rehrl… - Angewandte Chemie …, 2021 - Wiley Online Library
In multistep continuous flow chemistry, studying complex reaction mixtures in real time is a
significant challenge, but provides an opportunity to enhance reaction understanding and …

Designs of continuous-flow pharmaceutical crystallizers: developments and practice

M Jiang, RD Braatz - CrystEngComm, 2019 - pubs.rsc.org
Crystallization is an effective, low-cost purification & formulation process widely applied to
pharmaceuticals and fine chemicals. This review describes recent advances in research on …

Understanding flow chemistry for the production of active pharmaceutical ingredients

AS Burange, SM Osman, R Luque - Iscience, 2022 - cell.com
Multi-step organic syntheses of various drugs, active pharmaceutical ingredients, and other
pharmaceutically and agriculturally important compounds have already been reported using …

Analysis of crystal size dispersion effects in a continuous coiled tubular crystallizer: experiments and modeling

L Hohmann, T Greinert, O Mierka, S Turek… - Crystal Growth & …, 2018 - ACS Publications
Continuous processing gains importance in the fine chemical and pharmaceutical industries
where crystallization is an important downstream operation. Seeded cooling crystallization …

Continuous Generation of Gas‐Water Slugs with Improved Size Uniformity at a Tunable Scale

M Mou, L dela Rosa, JH Mugumya… - Chemical Engineering …, 2023 - Wiley Online Library
Slug flow has received increased interest due to the slugs serving as individual
microreactors for enhanced process efficiency and product quality. In this study, slugs were …

Mercaptan adsorption for desulfurization using a batch microprocess

A Mohammadi, A Azizzadeh, F Raji - Separation Science and …, 2023 - Taylor & Francis
In this study, a batch microprocess was developed for the adsorption of ethanethiol from
petroleum gas (LPG), liquefied at− 45° C. This process involved microdevices with ZSM-5 …

Handling of solids and flow characterization in a baffleless oscillatory flow coil reactor

BJ Doyle, B Gutmann, M Bittel, T Hubler… - Industrial & …, 2019 - ACS Publications
The solid handling ability and flow patterns of a baffleless oscillatory flow coil reactor are
investigated and characterized. Previous works in oscillatory flow have been generally …