Antibody‐incorporated nanomedicines for cancer therapy

SY Wu, FG Wu, X Chen - Advanced Materials, 2022 - Wiley Online Library
Antibody‐based cancer therapy, one of the most significant therapeutic strategies, has
achieved considerable success and progress over the past decades. Nevertheless …

Liposomes for drug delivery: review of vesicular composition, factors affecting drug release and drug loading in liposomes

S Pande - Artificial Cells, Nanomedicine, and Biotechnology, 2023 - Taylor & Francis
Liposomes are considered among the most versatile and advanced nanoparticle delivery
systems used to target drugs to specific cells and tissues. Structurally, liposomes are sphere …

Functionalized reduced graphene oxide as a versatile tool for cancer therapy

BS Dash, G Jose, YJ Lu, JP Chen - International journal of molecular …, 2021 - mdpi.com
Cancer is one of the deadliest diseases in human history with extremely poor prognosis.
Although many traditional therapeutic modalities—such as surgery, chemotherapy, and …

[HTML][HTML] Surface-modified lipid nanocarriers for crossing the blood-brain barrier (BBB): A current overview of active targeting in brain diseases

MI Teixeira, CM Lopes, MH Amaral, PC Costa - Colloids and Surfaces B …, 2023 - Elsevier
The blood-brain barrier (BBB) restricts the access of therapeutic agents to the brain,
complicating the treatment of neurological diseases, such as Alzheimer's disease (AD) …

Molecular mechanisms of drug resistance in glioblastoma

MA Dymova, EV Kuligina, VA Richter - International journal of molecular …, 2021 - mdpi.com
Glioblastoma multiforme (GBM) is the most common and fatal primary brain tumor, is highly
resistant to conventional radiation and chemotherapy, and is not amenable to effective …

Magnetic and GRPR-targeted reduced graphene oxide/doxorubicin nanocomposite for dual-targeted chemo-photothermal cancer therapy

BS Dash, YJ Lu, HA Chen, CC Chuang… - Materials Science and …, 2021 - Elsevier
Herein, we design a rGO-based magnetic nanocomposite by decorating rGO with citrate-
coated magnetic nanoparticles (CMNP). The magnetic rGO (mrGO) was modified by …

Liposomal IR-780 as a highly stable nanotheranostic agent for improved photothermal/photodynamic therapy of brain tumors by convection-enhanced delivery

YJ Lu, CC Chuang, JP Chen - Cancers, 2021 - mdpi.com
Simple Summary To improve the use of hydrophobic photosensitizer IR-780 in
photothermal/photodynamic therapy (PTT/PDT), we entrap IR-780 within the lipid bilayer of …

Biology of GD2 ganglioside: implications for cancer immunotherapy

P Machy, E Mortier, S Birklé - Frontiers in Pharmacology, 2023 - frontiersin.org
Part of the broader glycosphingolipid family, gangliosides are composed of a ceramide
bound to a sialic acid-containing glycan chain, and locate at the plasma membrane …

Combination drug loaded lipid-based nanocarriers as treatment entity for battling glioblastoma multiforme

Z Qamar, A Sartaj, MK Iqubal, FF Qizilbash… - Journal of Drug Delivery …, 2023 - Elsevier
Glioblastoma multiform (GBM) is the most lethal form of brain cancer pigeonholed by a high
rate of reoccurrence and poor diagnosis. Among all treatment strategies available …

Highly specific blood-brain barrier transmigrating single-domain antibodies selected by an in vivo phage display screening

SI Aguiar, JNR Dias, AS André, ML Silva, D Martins… - Pharmaceutics, 2021 - mdpi.com
A major bottleneck in the successful development of central nervous system (CNS) drugs is
the discovery and design of molecules that can cross the blood-brain barrier (BBB). Nano …