The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling
pathway was discovered more than a quarter-century ago. As a fulcrum of many vital cellular …

Introduction Chronic hand eczema (CHE) is a highly prevalent, burdensome condition
associated with functional impairment. Currently, topical therapeutics are the mainstay of …

DISCUSSION Two patients with CHE were successfully treated with baricitinib as
demonstrated by a decrease in clinical symptoms and improvement in quality of life. The …

Introduction Atopic dermatitis (AD) is a chronic, inflammatory skin condition mediated by
cytokines that utilize the Janus Kinase/Signal Transducer and Activator of Transcription (JAK …

Hand eczema is a chronic condition that affects an estimated 14.5% of the general
population. It has severe quality of life ramifications in those that struggle with it, including …

Introduction Chronic hand eczema (CHE) is a frequent skin disorder affecting up to 10% of
the population and strongly reduces Quality of Life (QoL). The first-line therapeutic strategies …

Treatment of chronic hand eczema with dupilumab-A retrospective follow-up study Treatment of
chronic hand eczema with dupilumab-A retrospective follow-up study J Eur Acad Dermatol …

Introduction Hand eczema is a chronic inflammatory skin disease characterized by
significant prevalence and impact on patients' Quality of Life (QoL). Because of its complex …

Chronic hand eczema (CHE) is a common inflammatory skin condition that significantly
impacts the quality of life. From work-related disabilities to social embarrassment, pain, and …

Retinoids are a frequently used class of drugs in the treatment of inflammatory as well as
malignant skin diseases. Retinoids have differential affinity for the retinoic acid receptor …