Myocardial ischemia is a disease with high morbidity and mortality, for which reperfusion is
currently the standard intervention. However, the reperfusion may lead to further myocardial …

Cardiovascular diseases (CVDs) are a significant health burden with an ever-increasing
prevalence. They remain the leading causes of morbidity and mortality worldwide. The use …

Background: Myocardial ischemia-reperfusion (I/R) injury causes cardiac dysfunction to
myocardial cell loss and fibrosis. Prevention of cell death is important to protect cardiac …

Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality. Reperfusion
strategies are the current standard therapy for AMI. However, they may result in paradoxical …

Editor's note: An article reporting one year of follow-up in the TASTE trial (Lagerqvist B,
Fröbert O, Olivecrona GK, et al. Outcomes 1 year after thrombus aspiration for myocardial …

Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

Acute myocardial infarction (MI) is a major cause of mortality and disability worldwide. In
patients with MI, the treatment option for reducing acute myocardial ischemic injury and …

Carotenoids are a class of natural, fat-soluble pigments found principally in plants. They
have potential antioxidant biological properties because of their chemical structure and …

Magnesium is the fourth most abundant cation in the body and the second most abundant
intracellular cation. It plays an important role in different organ systems at the cellular and …

Background Experimental evidence suggests that cyclosporine, which inhibits the opening
of mitochondrial permeability-transition pores, attenuates lethal myocardial injury that occurs …