Role played by signalling pathways in overcoming BRAF inhibitor resistance in melanoma
The discovery of the BRAFV600E mutation led to the development of vemurafenib
(PLX4032), a selective BRAF inhibitor specific to the kinase, for the treatment of metastatic …
(PLX4032), a selective BRAF inhibitor specific to the kinase, for the treatment of metastatic …
UVB-stimulated TNFα release from human melanocyte and melanoma cells is mediated by p38 MAPK
V Muthusamy, TJ Piva - International Journal of Molecular Sciences, 2013 - mdpi.com
Ultraviolet (UV) radiation activates cell signaling pathways in melanocytes. As a result of
altered signaling pathways and UV-induced cellular damage, melanocytes can undergo …
altered signaling pathways and UV-induced cellular damage, melanocytes can undergo …
Adjuvant therapy for cutaneous melanoma
D Schuitevoerder, CC Vining… - Surgical Oncology …, 2020 - surgonc.theclinics.com
Per the National Cancer Institute Web site, adjuvant therapy is defined as any
chemotherapy, radiation, targeted, hormone, or biologic therapy given after the primary …
chemotherapy, radiation, targeted, hormone, or biologic therapy given after the primary …
[PDF][PDF] The effect of antioxidants on UV-irradiated melanocytes and melanoma cells
A Banjar - 2015 - core.ac.uk
Ultraviolet radiation (UVR) plays an important a role in melanmaogenesis. This may occur
by inducing reactive oxygen species (ROS) formation in melanocytes however, antioxidants …
by inducing reactive oxygen species (ROS) formation in melanocytes however, antioxidants …