Simple Summary Breast cancer is the most common cancer among women. It is estimated
that 2.3 million new cases of BC are diagnosed globally each year. Based on mRNA gene …

Triple-negative breast cancer (TNBC) accounts for 15% to 20% of breast cancer cases and
is characterized by the absence of estrogen, progesterone, and human epidermal growth …

Triple-negative breast cancer (TNBC) is associated with an increased risk of early
recurrence and distant metastasis, as well as the development of therapeutic resistance and …

TP53 is the most frequently mutated gene in breast cancer, but its role in survival is
confounded by different studies concluding that TP53 mutations are associated with …

Breast cancer is an intrinsically heterogeneous disease. In the world about 1 million cases of
breast cancer are diagnosed annually and more than 170000 are triple-negative …

Worldwide, breast cancer is the most commonly diagnosed cancer among women and is the
leading cause of female cancer deaths. Zinc (Zn) functions as an antioxidant and plays a …

Background: Quantitative differences in biomarker expression relative to age and molecular
subtypes have not been well documented in invasive breast cancer (IBCA). Methods …

Mutations in TP53 lead to a defective G1 checkpoint and the dependence on checkpoint
kinase 1 (Chk1) for G2 or S phase arrest in response to DNA damage. In preclinical studies …

Objective Apocrine carcinoma, a subtype of invasive ductal carcinoma of the breast,
expresses androgen receptor (AR), but often lacks estrogen receptor (ER) and progesterone …

Abstract Tumor protein 53 (TP53) is a tumor suppressor gene that encodes tumor protein
p53. Tumor protein p53 regulates the expression of target genes in response to cellular …