Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …

Developing skeletal muscles express unique myosin isoforms, including embryonic and
neonatal myosin heavy chains, coded by the myosin heavy chain 3 (MYH3) and MYH8 …

Myofibrillar proteins exist as multiple isoforms that derive from multigene (isogene) families.
Additional isoforms, including products of tropomyosin, myosin light chain 1 fast, troponin T …

Contractile and energetic properties of human skeletal muscle have been studied for many
years in vivo in the body. It has been, however, difficult to identify the specific role of muscle …

abstract Mammalian skeletal muscle is an extremely heterogeneous tissue, composed of a
large variety of fiber types. These fibers, however, are not fixed units but represent highly …

▪ Abstract Striated muscle is an intricate, efficient, and precise machine that contains
complex interconnected cytoskeletal networks critical for its contractile activity. The …

We have examined the development of specific muscle fiber types in zebrafish axial muscle
by labeling myogenic precursor cells with vital fluorescent dyes and following their …

Although rachitic/osteomalacic myopathy caused by impaired vitamin D actions has long
been described, the molecular pathogenesis remains elusive. To determine physiological …

We assessed viable Pax7−/− mice in 129Sv/J background and observed reduced growth
and marked muscle wasting together with a complete absence of functional satellite cells …

Myocardial infarcts heal by scarring because myocardium cannot regenerate. To determine
if skeletal myoblasts could establish new contractile tissue, hearts of adult inbred rats were …