Phosphate anions are one of the most important constituents of living systems. Together with
heterocyclic bases and sugars, phosphates make up DNA, the hereditary element of living …

Background Convective dialysis modalities (haemofiltration (HF), haemodiafiltration (HDF),
and acetate‐free biofiltration (AFB)) removed excess body fluid across the dialysis …

BACKGROUND: Hyperphosphatemia is an independent risk factor for all-cause and
cardiovascular mortality in hemodialysis (HD) patients. Phosphate control often is …

Dialysis treatment has improved the survival of patients with kidney failure. However, the
hospitalization and mortality rates remain alarmingly high, primarily due to incomplete …

Background Intensive hemodialysis (HD) may have significant benefits. Recently, the role of
extended hemodiafiltration (HDF) has gained interest. The aim of this study was to evaluate …

Hyperphosphatemia is highly prevalent in hemodialysis (HD) and peritoneal dialysis (PD)
patients and is a major risk factor for cardiovascular mortality. Elimination of inorganic …

Background: Controlled randomised studies to prove improved cardiovascular stability and
improved anaemia management during on-line haemodiafiltration (oHDF) are scarce …

Phosphorus is an essential micromineral with a key role in cellular metabolism and tissue
structure. Serum phosphorus is maintained in a homeostatic range by the intestines, bones …

The treatment of hyperphosphatemia remains challenging in patients receiving
hemodialysis. This phase 1b study assessed safety and efficacy of EOS789, a novel pan …

Derangements of mineral metabolism occur during the early stages of chronic kidney
disease (CKD). Hyperphosphatemia develops in the majority of patients with ESRD and has …