Thyroid function in critically ill patients

E Fliers, AC Bianco, L Langouche… - The lancet Diabetes & …, 2015 - thelancet.com
Patients in the intensive care unit (ICU) typically present with decreased concentrations of
plasma tri-iodothyronine, low thyroxine, and normal range or slightly decreased …

Life-threatening thyrotoxicosis: thyroid storm

HB Burch, L Wartofsky - Endocrinology and metabolism clinics of North …, 1993 - Elsevier
Thyroid storm is a dreaded, fortunately rare complication of a very common disorder. Most
cases of thyroid storm occur following a precipitating event or intercurrent illness. Effective …

Thyrotoxicosis in patients with COVID-19: the THYRCOV study

A Lania, MT Sandri, M Cellini, M Mirani… - European journal of …, 2020 - academic.oup.com
Objective This study assessed thyroid function in patients affected by the coronavirus
disease-19 (COVID-19), based on the hypothesis that the cytokine storm associated with …

Non-thyroidal illness in the ICU: a syndrome with different faces

G Van den Berghe - Thyroid, 2014 - liebertpub.com
Background: Critically ill patients typically present with low or low-normal plasma thyroxine,
low plasma triiodothyronine (T3), increased plasma reverse T3 (rT3) concentrations, in the …

The pathophysiologic roles of interleukin-6 in human disease

DA Papanicolaou, RL Wilder… - Annals of internal …, 1998 - acpjournals.org
Interleukin-6, an inflammatory cytokine, is characterized by pleiotropy and redundancy of
action. Apart from its hematologic, immune, and hepatic effects, it has many endocrine and …

[HTML][HTML] Pitfalls in the measurement and interpretation of thyroid function tests

O Koulouri, C Moran, D Halsall, K Chatterjee… - Best practice & research …, 2013 - Elsevier
Thyroid function tests (TFTs) are amongst the most commonly requested laboratory
investigations in both primary and secondary care. Fortunately, most TFTs are …

Pathophysiologic response to severe burn injury

MG Jeschke, DL Chinkes, CC Finnerty, G Kulp… - Annals of …, 2008 - journals.lww.com
Objective: To improve clinical outcome and to determine new treatment options, we studied
the pathophysiologic response postburn in a large prospective, single center, clinical trial …

Effects of stress on the immune system

DN Khansari, AJ Murgo, RE Faith - Immunology today, 1990 - Elsevier
Stress, distress and a variety of psychiatric illnesses, notably the affective disorders, are
increasingly reported to be associated with immunosuppression. The concept that psychic …

The renal manifestations of thyroid disease

LH Mariani, JS Berns - Journal of the American Society of …, 2012 - journals.lww.com
Thyroid hormones influence renal development, kidney structure, renal hemodynamics,
GFR, the function of many transport systems along the nephron, and sodium and water …

Major depression and activation of the inflammatory response system

M Maes - Cytokines, stress, and depression, 1999 - Springer
Contemporary models of major depression emphasize the role of hypothalamic-pituitary-
adrenal (HPA)-axis hyperactivity and of dysfunctions in the turnover of serotonin (5-HT) or …