Abstract T cell factor‐1 (TCF‐1)(encoded by the TCF7 gene) is a transcription factor that
plays important role during the T cell development and differentiation for T cell to exercise its …

Osteosarcoma (OS) is the most common form of primary bone tumor affecting mainly
children and young adults. Despite therapeutic progress, the 5-year survival rate is 70%, but …

Hypoxia-induced decrease in cisplatin (CDDP) sensitivity in human osteosarcoma (OS) is a
significant obstacle to effective chemotherapy. Recently, mitophagy has been shown to be …

The interplay between immune cells/macrophages and fibroblast‐like synoviocytes (FLSs)
plays a pivotal role in initiating synovitis; however, their involvement in metabolic disorders …

Glucose metabolism is an essential process for energy production and cell survival for both
normal and abnormal cellular metabolism. Several glucose transporter/solute carrier 2A …

The major challenges in Osteosarcoma (OS) therapy are its heterogeneity and drug
resistance. The development of new therapeutic approaches to overcome the major growth …

Chondrosarcoma (CHS) is the second most common bone malignancy with limited
therapeutic approaches. Our previous study has found that Yes associated protein 1 (YAP1) …

Background T cell factor‐1 (TCF‐1)+ stem‐like tumor‐infiltrating lymphocytes (stem‐like
TILs) are important memory cells in the tumor microenvironment. However, their relationship …

A safer and more effective combination strategy designed to enhance the efficacy and
minimize the toxicity of cisplatin in osteosarcoma (OS) is urgently needed. Zeylenone (zey) …

Detailed analysis of the regulatory mechanism of spermatogonia stem cell (SSCs) genesis
can provide a novel strategy for the application of SSCs in the fields of transgenic animal …