Cystic kidneys are common causes of end-stage renal disease, both in children and in
adults. Autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive …

Autosomal recessive polycystic kidney disease (ARPKD) is a hepatorenal fibrocystic
disorder that is characterized by enlarged kidneys with progressive loss of renal function …

Early and severe forms of polycystic kidney disease (PKD) do already manifest during
childhood or adolescence. They are characterized by enlarged kidneys and diminished …

ARPKD is a genetically inherited kidney disease that manifests by bilateral enlargement of
cystic kidneys and liver fibrosis. It shows a range of severity, with 30% of individuals dying …

Autosomal recessive polycystic kidney disease (ARPKD) is a severe, typically early onset
form of renal cystic disease. The care of ARPKD patients has traditionally been the purview …

Renal cystic diseases encompass a broad group of disorders with variable phenotypic
expression. Cystic disorders can present during infancy, childhood, or adulthood. Often, but …

Autosomal recessive polycystic kidney disease (OMIM 263200) is a serious condition of the
kidney and liver caused by mutations in a single gene, PKHD1. This gene encodes …

Background Autosomal recessive polycystic kidney disease (ARPKD) is a rare but frequently
severe disorder that is typically characterized by cystic kidneys and congenital hepatic …

Mutation of the Cys1 gene underlies the renal cystic disease in the Cys1 cpk/cpk (cpk)
mouse that phenocopies human autosomal recessive polycystic kidney disease (ARPKD) …

Polycystic kidney disease (PKD) is one of the most common life-threatening genetic
diseases. Jared J. Grantham, MD, has done more than any other individual to promote PKD …