Although uncommon, the hypothalamic hamartoma (HH) is often associated with a
devastating clinical syndrome, which may include refractory epilepsy, progressive cognitive …

Lennox–Gastaut Syndrome (LGS) is a category of severe, disabling epilepsy, characterized
by frequent, treatment-resistant seizures, and cognitive impairment. Electroencephalography …

BACKGROUND AND PURPOSE: Reports of MR imaging in hypothalamic hamartomas
associated with epilepsy are few, and the number of patients studied is small. We aimed to …

Hypothalamic hamartomas may be associated with gelastic seizures, focal seizures, and a
generalized epileptic encephalopathy, with severe seizures and cognitive and behavior …

Purpose: To present the results of transcallosal surgical resection of hypothalamic
hamartoma (HH) in 26 patients with refractory epilepsy in a prospective outcome study …

Patients having a hypothalamic hamartoma (HH) frequently present gelastic or dacrystic
seizures, and they often later experience multiple additional seizure types which lead to a …

Objective To identify brain regions underlying interictal generalized paroxysmal fast activity
(GPFA), and their causal interactions, in children and adults with Lennox-Gastaut syndrome …

Background: Hypothalamic hamartomas (HHs), rare developmental abnormalities of the
inferior hypothalamus, often cause refractory, symptomatic, mixed epilepsy, including …

Hypothalamic hamartomas present with isolated fits of ictal laughter (gelastic epilepsy) or a
combination of gelastic and other types of seizures. Many of these patients also suffer from …

ABSTRACT A variety of surgical treatments for intractable epilepsy with hypothalamic
hamartoma (HH) are described, although most are derived from limited patient experience …