The possible link between hIAPP accumulation and β-cell death in diabetic patients has
inspired numerous studies focusing on amyloid structures and aggregation pathways of this …

Integral membrane proteins (IMPs) fulfill important physiological functions by providing cell–
environment, cell–cell and virus–host communication; nutrients intake; export of toxic …

How the epidermal growth factor receptor (EGFR) activates is incompletely understood. The
intracellular portion of the receptor is intrinsically active in solution, and to study its …

The receptor binding and proteolysis of Spike of SARS-CoV-2 release its S2 subunit to
rearrange and catalyze viral-cell fusion. This deploys the fusion peptide for insertion into the …

Supported lipid bilayers (SLBs) are cell-membrane-mimicking platforms that can be formed
on solid surfaces and integrated with a wide range of surface-sensitive measurement …

Many immune system receptors signal through cytoplasmic tyrosine-based motifs (ITAMs),
but how receptor ligation results in ITAM phosphorylation remains unknown. Live-cell …

HIV-1 envelope spike (Env) is a type I membrane protein that mediates viral entry. We used
nuclear magnetic resonance to determine an atomic structure of the transmembrane (TM) …

Receptor clustering on the cell membrane is critical in the signaling of many
immunoreceptors, and this mechanism has previously been attributed to the extracellular …

Surfactants are surface-active, amphiphilic compounds that are water-soluble in the micro-to
millimolar range, and self-assemble to form micelles or other aggregates above a critical …

The use of residual dipolar couplings (RDCs) in the analysis of biomolecular structure and
dynamics has expanded rapidly since its potential as a source of structural information on …