Mutation of the KRAS oncogene in pancreatic cancer is responsible for permanent activation
of the P21 RAS protein and the cascade of signalling pathways. Consequently, multiple …

Pancreatic cancer is one of the dreaded malignancies for both the patient and the clinician.
The five-year survival rate of pancreatic adenocarcinoma (PDA) is as low as 2% despite …

To identify predictive molecular markers for gemcitabine resistance, we investigated
changes in the expression of four genes associated with gemcitabine transport and …

It has been thought that there is a strong relationship between inflammation and
carcinogenesis so that the development of cancer occurs with chronic inflammation in many …

Background & Aims: K-ras mutation is frequently detected in pancreatic juice of patients with
pancreatic small cystic lesions, as well as those with pancreatic cancer. Those cystic lesions …

Since it was developed in 1992, endoscopic ultrasound‐guided fine needle aspiration (EUS‐
FNA) has been widely used and has been adapted for gastrointestinal and …

VOLUME 60, NO. 2, 2004 GASTROINTESTINAL ENDOSCOPY 267 cytologic brushing is as
high as 11% for the biliary tree and 21% for pancreatic strictures. 11, 12, 30 This morbidity …

Background Differential diagnosis of pancreatic solid masses with EUS-guided FNA (EUS-
FNA) is still challenging in about 15% of cases. Mutation of the K-ras gene is present in over …

BACKGROUND: The aim of this study was to evaluate the efficacy and the safety of the
covered Wallstent, a commercially available silicone-covered, self-expandable metallic stent …

BACKGROUND: Despite advances in diagnostic imaging techniques, the differentiation
between pancreatic cancer and focal pancreatitis remains difficult. This study evaluated the …