Two decades of epidemiological research shows that silent cerebrovascular disease is
common and is associated with future risk for stroke and dementia. It is the most common …

The term cerebral small vessel disease refers to a group of pathological processes with
various aetiologies that affect the small arteries, arterioles, venules, and capillaries of the …

The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the …

In making treatment decisions, doctors and patients must take into account relevant
randomised controlled trials (RCTs) and systematic reviews. Relevance depends on …

1.1. Organization of Committee and Evidence Review (UPDATED) For new or updated text,
view the 2011 Focused Update and the 2011 Update on Dabigatran. Text supporting …

The aim of this new statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of ischemic stroke among survivors of ischemic stroke …

Atrial fibrillation (AF) is the most common sustained cardiac rhythm disturbance, increasing
in prevalence with age. AF is often associated with structural heart disease, although a …

The antiphospholipid syndrome (APS) is defined by the presence of thrombosis and/or
pregnancy morbidity in combination with the persistent presence of circulating …

Background Despite the use of antiplatelet agents, usually aspirin, in patients who have had
an ischemic stroke, there is still a substantial rate of recurrence. Therefore, we investigated …

Atrial fibrillation (AF), the most common sustained cardiac rhythm disturbance, is increasing
in prevalence as the population ages. Although it is often associated with heart disease, AF …