[HTML][HTML] On a highway to the brain: A review on nose-to-brain drug delivery using nanoparticles

ML Formica, DA Real, ML Picchio, E Catlin… - Applied Materials …, 2022 - Elsevier
The administration of drugs to the central nervous system (CNS) is primarily controlled by
the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds …

Approved nanomedicine against diseases

Y Jia, Y Jiang, Y He, W Zhang, J Zou, KT Magar… - Pharmaceutics, 2023 - mdpi.com
Nanomedicine is a branch of medicine using nanotechnology to prevent and treat diseases.
Nanotechnology represents one of the most effective approaches in elevating a drug's …

[HTML][HTML] Nanosuspensions technology as a master key for nature products drug delivery and in vivo fate

Y Ma, Z Cong, P Gao, Y Wang - European Journal of Pharmaceutical …, 2023 - Elsevier
The drug nanosuspensions is a universal formulation approach for improved drug delivery
of hydrophobic drugs and one the most promising approaches for increasing the …

[HTML][HTML] Trilayer dissolving polymeric microneedle array loading Rose Bengal transfersomes as a novel adjuvant in early-stage cutaneous melanoma management

S Demartis, QK Anjani, F Volpe-Zanutto… - International Journal of …, 2022 - Elsevier
Melanoma remains a global concern, but current therapies present critical limitations
pointing out the urgent need for novel strategies. Among these, the cutaneous delivery of …

Formulation strategies of nanosuspensions for various administration routes

SG Pınar, AN Oktay, AE Karaküçük, N Çelebi - Pharmaceutics, 2023 - mdpi.com
Nanosuspensions (NSs), which are nanosized colloidal particle systems, have recently
become one of the most interesting substances in nanopharmaceuticals. NSs have high …

Ring inserts as a useful strategy to prepare tip-loaded microneedles for long-acting drug delivery with application in HIV pre-exposure prophylaxis

AJ Paredes, AD Permana, F Volpe-Zanutto, MN Amir… - Materials & …, 2022 - Elsevier
The role of microneedle array patches (MAPs) and, in particular, dissolving MAPs in
transdermal drug delivery has increased exponentially over the last decade. MAPs are able …

Polymeric and non-polymeric oxaliplatin nanomedicine for cancer therapy: A comprehensive review

M Pourmadadi, M Shaghaghi, R Arshad… - European Polymer …, 2024 - Elsevier
The importance of polymeric and non-polymeric Oxaliplatin (OXA) nanomedicine in cancer
therapy takes center stage in this article. OXA, a chemotherapy agent deployed in the …

Microneedle‐assisted transdermal delivery of nanoparticles: Recent insights and prospects

AJ Guillot, M Martínez‐Navarrete… - Wiley …, 2023 - Wiley Online Library
Transdermal delivery of drugs offers an interesting alternative for the administration of
molecules that present certain troubles when delivered by the oral route. It can produce …

[HTML][HTML] Development of dissolving microneedles for intradermal delivery of the long-acting antiretroviral drug bictegravir

C Zhang, LK Vora, IA Tekko, F Volpe-Zanutto… - International journal of …, 2023 - Elsevier
Oral administration and intramuscular (IM) injection are commonly recommended options for
human immunodeficiency virus (HIV) treatment. However, poor patient compliance due to …

Skin permeation of curcumin nanocrystals: Effect of particle size, delivery vehicles, and permeation enhancer

H Xiang, S Xu, W Zhang, Y Li, Y Zhou, X Miao - Colloids and Surfaces B …, 2023 - Elsevier
Nanocrystals are characterized by high drug loading, low carrier toxicity, and great structural
stability. Therefore, they are a promising and versatile strategy for enhancing the local …