Current and future potential of metallo drugs: Revisiting DNA-binding of metal containing molecules and their diverse mechanism of action

M Zaki, F Arjmand, S Tabassum - Inorganica Chimica Acta, 2016 - Elsevier
Cancer treatments regimes which include conventional chemotherapy have not proved so
successful in curing human malignancies. Failures to these treatment modalities include …

Coordination compounds of biogenic metals as cytotoxic agents in cancer therapy

DA Guk, OO Krasnovskaya… - Russian Chemical …, 2021 - iopscience.iop.org
The review summarizes the data on the structures and methods for the synthesis of
compounds with anticancer activity based on biogenic metals, which can replace platinum …

New Cu (II), Co (III) and Ni (II) metal complexes based on ONO donor tridentate hydrazone: Synthesis, structural characterization, and investigation of some biological …

A Zülfikaroğlu, ÇY Ataol, E Çelikoğlu… - Journal of Molecular …, 2020 - Elsevier
Abstract New Cu (II), Co (III) and Ni (II) metal complexes of N'-(3-ethoxy-2-
hydroxybenzylidene) acetohydrazide (ehbahH 2) ligand derived from 3 …

Diversities in the chelation of aroylhydrazones towards cobalt (II) salts: synthesis, spectral characterization, crystal structure and some theoretical studies

NA Mangalam, MRP Kurup, E Suresh, S Kaya… - Journal of Molecular …, 2021 - Elsevier
Five cobalt complexes synthesized from two aroylhydrazones were characterized by
elemental analyses, thermogravimetric analysis, molar conductivity, magnetic susceptibility …

The synthesis, characterization, DNA/protein interaction, molecular docking and catecholase activity of two Co (II) complexes constructed from the aroylhydrazone …

Y Li, Y Li, X Liu, Y Yang, D Lin, Q Gao - Journal of Molecular Structure, 2020 - Elsevier
Abstract Two Co (II) complexes, Co (BBH) phenMeCN (1) and Co (BSH) phenMeCN
(2)(HBBH= benzophenone benzoyl hydrazone, HBSH= benzophenone salicylylhydrazone …

Synthesis, characterization and crystal structures of two pentagonal-bipyramidal Fe (III) complexes with dihydrazone of 2, 6-diacetylpyridine and Girard's T reagent …

K Anđelković, MR Milenković, A Pevec, I Turel… - Journal of Inorganic …, 2017 - Elsevier
In this work synthesis, characterization and crystal structures of two isothiocyanato Fe (III)
complexes with 2, 2′-[2, 6-pyridinediylbis (ethylidyne-1-hydrazinyl-2-ylidene)] bis [N, N, N …

Synthesis, characterization and antitumoral activity of new cobalt (II) complexes: Effect of the ligand isomerism on the biological activity of the complexes

SR Morcelli, ÉS Bull, WS Terra, RO Moreira… - Journal of Inorganic …, 2016 - Elsevier
The synthesis, physico-chemical characterization and cytotoxicity against five human
tumoral cell lines (THP-1, U937, Molt-4, Colo205 and H460) of three new cobalt (II) …

Multifunctional 1, 10-phenanthroline derivative and its metal complexes as an anti-Alzheimer's agent: structure-based drug design, synthesis, characterization and …

EHE Gladis, K Nagashri, A Suman… - Journal of Coordination …, 2020 - Taylor & Francis
N-Heterocycles are structural constituents of pharmaceuticals based on FDA approved
therapeutic agents with more than 60% of drugs containing N-heterocycles as building …

Seven-coordinated cobalt (II) complexes with 2, 6-diacetylpyridine bis (4-hydroxybenzoylhydrazone): synthesis, characterisation, DNA binding and cleavage …

R Gup, C Gökçe, N Dilek - Supramolecular Chemistry, 2015 - Taylor & Francis
Synthesis and characterisation of three seven-coordinated cobalt (II) complexes of 2, 6-
diacetylpyridine bis (4-hydroxybenzoylhydrazone)(H4L) ligand,[Co (H2L)(H2O) 2](1),[Co …

Synthesis, Crystal Structure and In Vitro Cytotoxicity of Novel Cu (II) Complexes Derived from Isatin Hydrazide-Hydrazone Ligands.

C Topkaya - Acta Chimica Slovenica, 2023 - search.ebscohost.com
In this study, two innovative hydrazine-hydrazone ligands were synthesized through the
chemical reaction involving the isatin moiety with 4-hydroxybenzohydrazide and …