Lipolysis: cellular mechanisms for lipid mobilization from fat stores
The perception that intracellular lipolysis is a straightforward process that releases fatty
acids from fat stores in adipose tissue to generate energy has experienced major revisions …
acids from fat stores in adipose tissue to generate energy has experienced major revisions …
Lipid and glucose metabolism in white adipocytes: pathways, dysfunction and therapeutics
In mammals, the white adipocyte is a cell type that is specialized for storage of energy (in the
form of triacylglycerols) and for energy mobilization (as fatty acids). White adipocyte …
form of triacylglycerols) and for energy mobilization (as fatty acids). White adipocyte …
Cytosolic lipolysis and lipophagy: two sides of the same coin
Fatty acids are the most efficient substrates for energy production in vertebrates and are
essential components of the lipids that form biological membranes. Synthesis of …
essential components of the lipids that form biological membranes. Synthesis of …
FAT SIGNALS-lipases and lipolysis in lipid metabolism and signaling
R Zechner, R Zimmermann, TO Eichmann… - Cell metabolism, 2012 - cell.com
Lipolysis is defined as the catabolism of triacylglycerols stored in cellular lipid droplets.
Recent discoveries of essential lipolytic enzymes and characterization of numerous …
Recent discoveries of essential lipolytic enzymes and characterization of numerous …
Role of lipids in the formation and maintenance of the cutaneous permeability barrier
KR Feingold, PM Elias - Biochimica et Biophysica Acta (BBA)-Molecular …, 2014 - Elsevier
The major function of the skin is to form a barrier between the internal milieu and the hostile
external environment. A permeability barrier that prevents the loss of water and electrolytes …
external environment. A permeability barrier that prevents the loss of water and electrolytes …
Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease
Lipolysis is the process by which triglycerides (TGs) are hydrolyzed to free fatty acids (FFAs)
and glycerol. In adipocytes, this is achieved by sequential action of adipose TG lipase …
and glycerol. In adipocytes, this is achieved by sequential action of adipose TG lipase …
[HTML][HTML] Lipolysis–a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores
A Lass, R Zimmermann, M Oberer, R Zechner - Progress in lipid research, 2011 - Elsevier
Lipolysis is the biochemical pathway responsible for the catabolism of triacylglycerol (TAG)
stored in cellular lipid droplets. The hydrolytic cleavage of TAG generates non-esterified fatty …
stored in cellular lipid droplets. The hydrolytic cleavage of TAG generates non-esterified fatty …
[HTML][HTML] The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes
Mammals store metabolic energy as triacylglycerols (TGs) in adipose tissue. TG synthesis is
catalyzed by the evolutionarily unrelated acyl-CoA: diacylglycerol acyltransferase (DGAT) …
catalyzed by the evolutionarily unrelated acyl-CoA: diacylglycerol acyltransferase (DGAT) …
Recent progress in phospholipase A2 research: from cells to animals to humans
M Murakami, Y Taketomi, Y Miki, H Sato… - Progress in lipid …, 2011 - Elsevier
Mammalian genomes encode genes for more than 30 phospholipase A2s (PLA2s) or
related enzymes, which are subdivided into several classes including low-molecular-weight …
related enzymes, which are subdivided into several classes including low-molecular-weight …
Ceramide synthesis in the epidermis
M Rabionet, K Gorgas, R Sandhoff - … Acta (BBA)-Molecular and Cell Biology …, 2014 - Elsevier
The epidermis and in particular its outermost layer the stratum corneum provides terrestrial
vertebrates with a pivotal defensive barrier against water loss, xenobiotics and harmful …
vertebrates with a pivotal defensive barrier against water loss, xenobiotics and harmful …