Mangiferin: An effective therapeutic agent against several disorders

S Du, H Liu, T Lei, X Xie, H Wang… - Molecular …, 2018 - spandidos-publications.com
Abstract Mangiferin (1, 3, 6, 7‑tetrahydroxyxanthone‑C2‑β‑D‑glucoside) is a bioactive
ingredient predominantly isolated from the mango tree, with potent antioxidant activity and …

Mango seed kernel: A bountiful source of nutritional and bioactive compounds

P Choudhary, TB Devi, S Tushir, RC Kasana… - Food and Bioprocess …, 2023 - Springer
Mango (Mangifera indica L.) is grown worldwide and widely accepted by consumers for its
sweet taste and exotic flavor. During consumption and processing of mango, a large quantity …

Mangiferin–a bioactive xanthonoid, not only from mango and not just antioxidant

A Matkowski, P Kus, E Goralska… - Mini reviews in …, 2013 - ingentaconnect.com
Mangiferin is a plant natural polyphenol of C-glycosylxanthone structure and various
pharmacological activities. It can be found in many plant species, among which the mango …

[HTML][HTML] Mangiferin and cancer: Mechanisms of action

F Gold-Smith, A Fernandez, K Bishop - Nutrients, 2016 - mdpi.com
Mangiferin, a bioactive compound derived primarily from Anacardiaceae and Gentianaceae
families and found in mangoes and honeybush tea, has been extensively studied for its …

Mangiferin prevents diabetic nephropathy progression and protects podocyte function via autophagy in diabetic rat glomeruli

X Wang, L Gao, H Lin, J Song, J Wang, Y Yin… - European Journal of …, 2018 - Elsevier
Diabetic nephropathy (DN) is one of the most severe microangiopathies of diabetes mellitus
and is a leading cause of end stage renal disease. Numerous studies suggest that podocyte …

Anti-inflammation and anti-pyroptosis activities of mangiferin via suppressing NF-κB/NLRP3/GSDMD signaling cascades

M Feng, S Wei, S Zhang, Y Yang - International Journal of Molecular …, 2022 - mdpi.com
Mangiferin (MF), a xanthone that extensively exists in many herbal medicines, processes
significant activities of anti-inflammation and immunomodulation. The potential regulatory …

Therapeutic potential of mangiferin in the treatment of various neuropsychiatric and neurodegenerative disorders

V Walia, SK Chaudhary, NK Sethiya - Neurochemistry international, 2021 - Elsevier
Xanthones are important chemical class of bioactive products that confers therapeutic
benefits. Of several xanthones, mangiferin is known to be distributed widely across several …

[HTML][HTML] Antioxidant activity of the mangiferin inclusion complex with β-cyclodextrin

F da Rocha Ferreira, IB Valentim, ELC Ramones… - LWT-Food Science and …, 2013 - Elsevier
The aim of this study was to characterize the complex between mangiferin (MGN) with β-
cyclodextrin (β-CD) obtained through the co-evaporation method using Differential Scanning …

Medicinal properties of mangiferin, structural features, derivative synthesis, pharmacokinetics and biological activities

O Benard, Y Chi - Mini reviews in medicinal chemistry, 2015 - ingentaconnect.com
The identification of biologically active and potentially therapeutically useful
pharmacophores from natural products has been a long-term focus in the pharmaceutical …

[HTML][HTML] Mangiferin ameliorates acetaminophen-induced hepatotoxicity through APAP-Cys and JNK modulation

A Chowdhury, J Lu, R Zhang, J Nabila, H Gao… - Biomedicine & …, 2019 - Elsevier
An overdose of the most popular analgesic, acetaminophen (APAP), is one of the leading
causes of acute liver failure. It is well established that glutathione is exhausted by APAP …