The surprising discovery that the diatomic gas nitric oxide (NO) is generated by mammalian
cells and serves to regulate a multitude of physiological processes has continued to …

Purpose: To review the physiologic role of nitric oxide, an unusual messenger molecule that
mediates blood vessel relaxation, neurotransmission, and pathogen suppression. Data …

A large body of research has been dedicated to the effects of gastrointestinal peptides on
vagal afferent fibres, yet multiple lines of evidence indicate that gastrointestinal peptides …

Background Aims: Impaired accommodation of the proximal stomach to a meal has been
reported in functional dyspepsia, but its relevance to symptoms is unclear. The aim of this …

High concentrations of nitrite present in saliva (derived from dietary nitrate) may, upon
acidification, generate nitrogen oxides in the stomach in sufficient amounts to provide …

Nitric oxide (NO) is a cytotoxic agent of macrophages, a messenger molecule of neurons,
and a vasodilator produced by endothelial cells. NO synthase, the synthetic enzyme for NO …

In the past ten years several research fields have converged to show that the tiny molecule
nitric oxide (NO), a reactive gas, functions both as a signalling molecule in endothelial and …

Infection by bacteria, parasites or viruses and tissue inflammation such as gastritis, hepatitis
and colitis are recognized risk factors for human cancers at various sites. Nitric oxide (NO) …

Nitric oxide (NO) is a free radical gas, clearly distinct from nitrous oxide, N20, which is used
as an anesthetic and is chemically stable. NO has long been known to occur in bacteria, but …

By homologous recombination, we have generated mice that lack the neuronal nitric oxide
synthase (NOS) gene. Neuronal NOS expression and NADPH-diaphorase (NDP) staining …