From animal poisons and venoms to medicines: achievements, challenges and perspectives in drug discovery
KCF Bordon, CT Cologna, EC Fornari-Baldo… - Frontiers in …, 2020 - frontiersin.org
Animal poisons and venoms are comprised of different classes of molecules displaying wide-
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …
Scorpion venom components that affect ion-channels function
V Quintero-Hernández, JM Jiménez-Vargas… - Toxicon, 2013 - Elsevier
The number and types of venom components that affect ion-channel function are reviewed.
These are the most important venom components responsible for human intoxication …
These are the most important venom components responsible for human intoxication …
Cell entry of cell penetrating peptides: tales of tails wagging dogs
Cell penetrating peptides hold considerable potential for academic and pharmaceutical
remits with an interest in delivering macromolecules to the insides of cells. Hundreds of …
remits with an interest in delivering macromolecules to the insides of cells. Hundreds of …
Cell penetrating peptides: classification, mechanisms, methods of study, and applications
A Gori, G Lodigiani, SG Colombarolli… - …, 2023 - Wiley Online Library
Cell‐penetrating peptides (CPPs) encompass a class of peptides that possess the
remarkable ability to cross cell membranes and deliver various types of cargoes, including …
remarkable ability to cross cell membranes and deliver various types of cargoes, including …
Chlorotoxin: Structure, activity, and potential uses in cancer therapy
Chlorotoxin is a disulfide‐rich stable peptide from the venom of the Israeli scorpion Leiurus
quinquestriatus, which has potential therapeutic applications in the treatment of cancer. Its …
quinquestriatus, which has potential therapeutic applications in the treatment of cancer. Its …
Endocytosis, intracellular traffic and fate of cell penetrating peptide based conjugates and nanoparticles
The insides of cells can be viewed as a treasure trove of targets for therapeutic intervention
of diseases or as deposits for contrasting agents. Increasingly the molecules that need to be …
of diseases or as deposits for contrasting agents. Increasingly the molecules that need to be …
Cell-penetrating peptides derived from animal venoms and toxins
G Rádis-Baptista - Toxins, 2021 - mdpi.com
Cell-penetrating peptides (CPPs) comprise a class of short polypeptides that possess the
ability to selectively interact with the cytoplasmic membrane of certain cell types, translocate …
ability to selectively interact with the cytoplasmic membrane of certain cell types, translocate …
Scorpion venomics: a 2019 overview
JI Cid-Uribe, JI Veytia-Bucheli… - Expert review of …, 2020 - Taylor & Francis
Introduction: A few scorpions are dangerous to humans. Their medical relevance was the
initial driving force for venom research. By classical biochemistry and molecular cloning …
initial driving force for venom research. By classical biochemistry and molecular cloning …
Venom proteomic and venomous glands transcriptomic analysis of the Egyptian scorpion Scorpio maurus palmatus (Arachnida: Scorpionidae)
MA Abdel-Rahman, V Quintero-Hernandez… - Toxicon, 2013 - Elsevier
Proteomic analysis of the scorpion venom Scorpio maurus palmatus was performed using
reverse-phase HPLC separation followed by mass spectrometry determination. Sixty five …
reverse-phase HPLC separation followed by mass spectrometry determination. Sixty five …
Classes of cell-penetrating peptides
During the three decades of cell-penetrating peptides era the superfamily of CPPs has
rapidly expanded, and the quest for new sequences continues. CPPs have been well …
rapidly expanded, and the quest for new sequences continues. CPPs have been well …