Trypanosoma cruzi genetic diversity: Something new for something known about Chagas disease manifestations, serodiagnosis and drug sensitivity
B Zingales - Acta tropica, 2018 - Elsevier
The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …
Between a bug and a hard place: Trypanosoma cruzi genetic diversity and the clinical outcomes of Chagas disease
LA Messenger, MA Miles, C Bern - Expert review of anti-infective …, 2015 - Taylor & Francis
Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
Genetic diversity of Trypanosoma cruzi in bats, and multilocus phylogenetic and phylogeographical analyses supporting Tcbat as an independent DTU (discrete …
L Lima, O Espinosa-Álvarez, PA Ortiz, JA Trejo-Varón… - Acta tropica, 2015 - Elsevier
Trypanosoma cruzi is a complex of phenotypically and genetically diverse isolates
distributed in six discrete typing units (DTUs) designated as TcI–TcVI. Five years ago, T …
distributed in six discrete typing units (DTUs) designated as TcI–TcVI. Five years ago, T …
One health–an ecological and evolutionary framework for tackling Neglected Zoonotic Diseases
JP Webster, CM Gower, SCL Knowles… - Evolutionary …, 2016 - Wiley Online Library
Understanding the complex population biology and transmission ecology of multihost
parasites has been declared as one of the major challenges of biomedical sciences for the …
parasites has been declared as one of the major challenges of biomedical sciences for the …
[HTML][HTML] Trypanosoma Cruzi Genome: Organization, Multi-Gene Families, Transcription, and Biological Implications
A Herreros-Cabello, F Callejas-Hernández, N Gironès… - Genes, 2020 - mdpi.com
Chagas disease caused by the parasite Trypanosoma cruzi affects millions of people.
Although its first genome dates from 2005, its complexity hindered a complete assembly and …
Although its first genome dates from 2005, its complexity hindered a complete assembly and …
[HTML][HTML] Hybridization in parasites: consequences for adaptive evolution, pathogenesis, and public health in a changing world
Hybridization of parasites is an emerging public health concern at the interface of infectious
disease biology and evolution. Increasing economic development, human migration, global …
disease biology and evolution. Increasing economic development, human migration, global …
[HTML][HTML] Molecular epidemiology of human oral Chagas disease outbreaks in Colombia
JD Ramírez, M Montilla, ZM Cucunubá… - PLoS neglected …, 2013 - journals.plos.org
Background Trypanosoma cruzi, the causative agent of Chagas disease, displays significant
genetic variability revealed by six Discrete Typing Units (TcI-TcVI). In this pathology, oral …
genetic variability revealed by six Discrete Typing Units (TcI-TcVI). In this pathology, oral …
[HTML][HTML] Fifteen Years after the Definition of Trypanosoma cruzi DTUs: What Have We Learned?
B Zingales, AM Macedo - Life, 2023 - mdpi.com
Trypanosoma cruzi, the protozoan causative of Chagas disease (ChD), exhibits striking
genetic and phenotypic intraspecific diversity, along with ecoepidemiological complexity …
genetic and phenotypic intraspecific diversity, along with ecoepidemiological complexity …
The compatibility between Biomphalaria glabrata snails and Schistosoma mansoni: an increasingly complex puzzle
This review reexamines the results obtained in recent decades regarding the compatibility
polymorphism between the snail, Biomphalaria glabrata, and the pathogen, Schistosoma …
polymorphism between the snail, Biomphalaria glabrata, and the pathogen, Schistosoma …
Contemporary cryptic sexuality in Trypanosoma cruzi
Clonal propagation is considered to be the predominant mode of reproduction among many
parasitic protozoa. However, this assumption may overlook unorthodox, infrequent or cryptic …
parasitic protozoa. However, this assumption may overlook unorthodox, infrequent or cryptic …