Point of care testing for infectious diseases

H Chen, K Liu, Z Li, P Wang - Clinica chimica acta, 2019 - Elsevier
Infectious diseases are caused by pathogenic microorganisms and can be transmitted
between individuals and populations thus threatening the general public health and …

[HTML][HTML] MicroRNA amplification and detection technologies: opportunities and challenges for point of care diagnostics

VP Dave, TA Ngo, AK Pernestig, D Tilevik, K Kant… - Laboratory …, 2019 - Elsevier
The volume of point of care (POC) testing continues to grow steadily due to the increased
availability of easy-to-use devices, thus making it possible to deliver less costly care closer …

CRISPR/Cas13a‐powered electrochemical microfluidic biosensor for nucleic acid amplification‐free miRNA diagnostics

R Bruch, J Baaske, C Chatelle, M Meirich… - Advanced …, 2019 - Wiley Online Library
Noncoding small RNAs, such as microRNAs, are becoming the biomarkers of choice for
multiple diseases in clinical diagnostics. A dysregulation of these microRNAs can be …

The potential of using blood circular RNA as liquid biopsy biomarker for human diseases

G Wen, T Zhou, W Gu - Protein & cell, 2021 - academic.oup.com
Circular RNA (circRNA) is a novel class of single-stranded RNAs with a closed loop
structure. The majority of circRNAs are formed by a back-splicing process in pre-mRNA …

Where metabolism meets senescence: focus on endothelial cells

J Sabbatinelli, F Prattichizzo, F Olivieri… - Frontiers in …, 2019 - frontiersin.org
Despite the decline in their proliferative potential, senescent cells display a high metabolic
activity. Senescent cells have been shown to acquire a more glycolytic state even in …

Highly multiplexed rapid DNA detection with single-nucleotide specificity via convective PCR in a portable device

D Khodakov, J Li, JX Zhang, DY Zhang - Nature Biomedical …, 2021 - nature.com
Assays for the molecular detection of nucleic acids are typically constrained by the level of
multiplexing (this is the case for the quantitative polymerase chain reaction (qPCR) and for …

MicroRNA biomarkers in IBD—differential diagnosis and prediction of colitis-associated cancer

JP James, LB Riis, M Malham, E Høgdall… - International journal of …, 2020 - mdpi.com
Inflammatory bowel disease (IBD) includes Crohn's disease (CD) and ulcerative colitis (UC).
These are chronic autoimmune diseases of unknown etiology affecting the gastrointestinal …

[HTML][HTML] Circulating microRNAs as emerging regulators of COVID-19

Y Liang, D Fang, X Gao, X Deng, N Chen, J Wu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the novel
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global pandemic that …

DNA nanotechnology approaches for microRNA detection and diagnosis

AR Chandrasekaran, JA Punnoose, L Zhou… - Nucleic acids …, 2019 - academic.oup.com
MicroRNAs are involved in the crucial processes of development and diseases and have
emerged as a new class of biomarkers. The field of DNA nanotechnology has shown great …

miR‐34b‐5p inhibition attenuates lung inflammation and apoptosis in an LPS‐induced acute lung injury mouse model by targeting progranulin

W Xie, Q Lu, K Wang, J Lu, X Gu, D Zhu… - Journal of cellular …, 2018 - Wiley Online Library
Inflammation and apoptosis play important roles in the initiation and progression of acute
lung injury (ALI). Our previous study has shown that progranulin (PGRN) exerts lung …