The powerful functions of peptide-based bioactive matrices for regenerative medicine

CM Rubert Pérez, N Stephanopoulos, S Sur… - Annals of biomedical …, 2015 - Springer
In an effort to develop bioactive matrices for regenerative medicine, peptides have been
used widely to promote interactions with cells and elicit desired behaviors in vivo. This paper …

Angiotensin receptor blockers and angiogenesis: clinical and experimental evidence

LM Willis, AB El-Remessy, PR Somanath… - Clinical …, 2011 - portlandpress.com
Angiotensin II type 1 receptor antagonists [ARBs (angiotensin receptor blockers)] are
indicated for BP (blood pressure)-lowering, renal protection and cardioprotection in patients …

Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis

F Finetti, A Basile, D Capasso, S Di Gaetano… - Biochemical …, 2012 - Elsevier
Vascular endothelial growth factor (VEGF) is the main regulator of physiological and
pathological angiogenesis. Low molecular weight molecules able to stimulate angiogenesis …

Mimicking the bioactivity of fibroblast growth factor-2 using supramolecular nanoribbons

CM Rubert Pérez, Z Álvarez, F Chen… - ACS biomaterials …, 2017 - ACS Publications
Fibroblast growth factor (FGF-2) is a multifunctional growth factor that has pleiotropic effects
in different tissues and organs. In particular, FGF-2 has a special role in angiogenesis, an …

Manipulation of endogenous kinase activity in living cells using photoswitchable inhibitory peptides

JJ Yi, H Wang, M Vilela, G Danuser… - ACS synthetic …, 2014 - ACS Publications
Optogenetic control of endogenous signaling can be an important tool for probing cell
behavior. Using the photoresponse of the LOV2 domain of Avena sativa phototropin 1, we …

Wnt/β-catenin regulates the activity of epiprofin/Sp6, SHH, FGF, and BMP to coordinate the stages of odontogenesis

M Aurrekoetxea, I Irastorza… - Frontiers in cell and …, 2016 - frontiersin.org
Background: We used an in vitro tooth development model to investigate the effects of
overactivation of the Wnt/β-catenin pathway during odontogenesis by bromoindirubin oxime …

Pro-angiogenic peptides in biomedicine

L De Rosa, R Di Stasi, LD D'Andrea - Archives of biochemistry and …, 2018 - Elsevier
Pro-angiogenic therapy provides a promising new perspective in tackling of many common
and severe pathological conditions, such as central and peripheral vascular diseases. Pro …

Bioinorganic aspects of angiogenesis

LD D'Andrea, A Romanelli, R Di Stasi… - Dalton Transactions, 2010 - pubs.rsc.org
Angiogenesis is a physiologic process characterized by the sprouting of a new blood vessel
from a pre-existing one. In mammalians the angiogenesis process is dormant, except for few …

Biofunctionalization of hydrogel-based scaffolds for vascular tissue regeneration

J López-Gutierrez, R Ramos-Payán… - Frontiers in …, 2023 - frontiersin.org
Congenital and acquired tissular losses due to disease or trauma are a major world health
problem. Regenerative therapy aims to fix damaged tissues by directing the natural capacity …

Characterization of a designed vascular endothelial growth factor receptor antagonist helical peptide with antiangiogenic activity in vivo

A Basile, A Del Gatto, D Diana, R Di Stasi… - Journal of medicinal …, 2011 - ACS Publications
Angiogenesis is a fundamental process underlining physiological and pathological
conditions. It is mainly regulated by the vascular endothelial growth factor (VEGF) and its …