Since the discovery of the first trypsinogen mutation in families with hereditary pancreatitis,
pancreatic genetics has made rapid progress. The identification of mutations in genes …

Premature activation of digestive enzymes in the pancreas has been linked to development
of pancreatitis for more than a century. Recent development of novel models to study the …

Chronic pancreatitis is a multifactorial, fibroinflammatory syndrome in which repetitive
episodes of pancreatic inflammation lead to extensive fibrotic tissue replacement, resulting …

Abstract Background The American College of Medical Genetics and Genomics (ACMG)-
recommended five variant classification categories (pathogenic, likely pathogenic, uncertain …

Food contaminants are challenging the food industry due to the inefficiency of conventional
decontamination techniques. Cold plasma as an emerging technique for the degradation of …

Acute pancreatitis (AP), an acute inflammatory disorder of the exocrine pancreas, is one of
the most common gastrointestinal diseases encountered in emergency departments with no …

Abstract The Toxic-metabolic, Idiopathic, Genetic, Autoimmune, Recurrent and severe acute
pancreatitis and Obstructive (TIGAR-O) Pancreatitis Risk/Etiology Checklist (TIGAR-O_V1) is …

Background & Aims Pancreatitis is characterized by acinar cell death and persistent
inflammation. Ferroptosis is a type of lipid peroxidation-dependent necrosis, which is …

Objectives: Rare pathogenic variants in the SPINK1, PRSS1, CTRC, and CFTR genes have
been strongly associated with a risk of developing chronic pancreatitis (CP). However, their …

Pancreatitis is regarded by clinicians as one of the most complicated and clinically
challenging of all disorders affecting the abdomen. It is classified on the basis of clinical …