Management of inflammation in cardiovascular diseases

SK Goswami, P Ranjan, RK Dutta, SK Verma - Pharmacological research, 2021 - Elsevier
Cardiovascular disease is the leading cause of morbidity and mortality world-wide. Recently,
the role of inflammation in the progression of diseases has significantly attracted …

Cardiovascular inflammaging: mechanisms and translational aspects

ML Barcena, M Aslam, S Pozdniakova, K Norman… - Cells, 2022 - mdpi.com
Aging is one of the major non-reversible risk factors for several chronic diseases, including
cancer, type 2 diabetes, dementia, and cardiovascular diseases (CVD), and it is a key cause …

Widespread coronary inflammation in unstable angina

A Buffon, LM Biasucci, G Liuzzo… - … England Journal of …, 2002 - Mass Medical Soc
Background Inflammation within vulnerable coronary plaques may cause unstable angina
by promoting rupture and erosion. In unstable angina, activated leukocytes may be found in …

Cardiovascular disease, interleukin-6, and risk of mortality in older women: the women's health and aging study

S Volpato, JM Guralnik, L Ferrucci, J Balfour… - Circulation, 2001 - Am Heart Assoc
Background—Systemic chronic inflammation has been found to be related to all-cause
mortality risk in older persons. We investigated whether specific chronic conditions …

Factors associated with plasma IL-6 levels during HIV infection

ÁH Borges, JL O'Connor, AN Phillips… - The Journal of …, 2015 - academic.oup.com
Abstract Background. Elevated interleukin 6 (IL-6) levels have been linked to cardiovascular
disease, cancer and death. Persons with human immunodeficiency virus (HIV) infection …

High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study

S Kinlay, GG Schwartz, AG Olsson, N Rifai, SJ Leslie… - Circulation, 2003 - Am Heart Assoc
Background—Inflammation promotes acute coronary syndromes and ensuing clinical
complications. Although statins reduce inflammatory markers in asymptomatic adults or in …

Clinical progression of incidental, asymptomatic lesions discovered during culprit vessel coronary intervention

R Glaser, F Selzer, DP Faxon, WK Laskey, HA Cohen… - Circulation, 2005 - Am Heart Assoc
Background—With the reduction in restenosis rates by drug-eluting stents, there is new
controversy concerning the optimal management of incidental, nontarget lesions identified …

Human CRP gene polymorphism influences CRP levels: implications for the prediction and pathogenesis of coronary heart disease

DJ Brull, N Serrano, F Zito, L Jones… - … , and vascular biology, 2003 - Am Heart Assoc
Objective—C-reactive protein (CRP) concentrations are predictive of cardiovascular
disease, and levels are heritable, in part. We identified novel polymorphisms in the CRP …

Preanalytic and analytic sources of variations in C-reactive protein measurement: implications for cardiovascular disease risk assessment

TB Ledue, N Rifai - Clinical Chemistry, 2003 - academic.oup.com
Background: C-reactive protein (CRP) is a widely recognized indicator of inflammation and
is known to play an important role in atherogenesis. Recent prospective studies have …

Inflammatory markers at the site of ruptured plaque in acute myocardial infarction: locally increased interleukin-6 and serum amyloid A but decreased C-reactive …

W Maier, LA Altwegg, R Corti, S Gay, M Hersberger… - Circulation, 2005 - Am Heart Assoc
Background—Acute myocardial infarction (AMI) is associated with inflammation. However, it
remains unclear whether it originates from the ruptured plaque or represents a systemic …