Targeting PARP proteins in acute leukemia: DNA damage response inhibition and therapeutic strategies
The members of the Poly (ADP‐ribose) polymerase (PARP) superfamily are involved in
several biological processes and, in particular, in the DNA damage response (DDR). The …
several biological processes and, in particular, in the DNA damage response (DDR). The …
Epigenetic and Molecular Alterations in Obesity: Linking CRP and DNA Methylation to Systemic Inflammation
Obesity is marked by excessive fat accumulation in the adipose tissue, which disrupts
metabolic processes and causes chronic systemic inflammation. Commonly, body mass …
metabolic processes and causes chronic systemic inflammation. Commonly, body mass …
In vivo imaging system (IVIS) therapeutic assessment of tyrosine kinase inhibitor-loaded gold nanocarriers for acute myeloid leukemia: a pilot study
Acute myeloid leukemia (AML) is a malignancy in the myeloid lineage that is characterized
by symptoms like fatigue, bleeding, infections, or anemia, and it can be fatal if untreated. In …
by symptoms like fatigue, bleeding, infections, or anemia, and it can be fatal if untreated. In …