Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …

Coagulase-negative Staphylococci (CoNS) are skin commensal bacteria. Besides their role
in maintaining homeostasis, CoNS have emerged as major pathogens in nosocomial …

Multidrug-resistant nosocomial pathogens present a major burden for hospitals. Rapid
cluster identification and pathogen profiling, ie, of antibiotic resistance and virulence genes …

The increasing prevalence of multidrug-resistant (MDR) bacteria is a serious global
challenge. Here, we studied prospectively whether bacterial whole-genome sequencing …

Bacterial ADP-ribosyltransferase toxins (bARTTs) transfer ADP-ribose to eukaryotic proteins
to promote bacterial pathogenesis. In this Review, we use prototype bARTTs, such as …

Microbial virulence is a complex and often multifactorial phenotype, intricately linked to a
pathogen's evolutionary trajectory. Toxicity, the ability to destroy host cell membranes, and …

Staphylococcus aureus is a major cause of bacteremia, which frequently results in serious
secondary infections such as infective endocarditis, osteomyelitis, and septic arthritis. The …

The availability of genome sequences obtained using next-generation sequencing (NGS)
has revolutionized the field of infectious diseases. Indeed, more than 38,000 bacterial and …

Genome-wide association studies (GWASs) have become an increasingly important
approach for eukaryotic geneticists, facilitating the identification of hundreds of genetic …

Staphylococcus aureus produces a high number of RNAs for which the functions are poorly
understood. Several non-coding RNAs carry a C-rich sequence suggesting that they …