Advanced nanomaterials-based electrochemical biosensors for catecholamines detection: challenges and trends

Z Fredj, M Sawan - Biosensors, 2023 - mdpi.com
Catecholamines, including dopamine, epinephrine, and norepinephrine, are considered
one of the most crucial subgroups of neurotransmitters in the central nervous system (CNS) …

[HTML][HTML] Phytotherapy: A promising approach for the treatment of Alzheimer's disease

OO John, IS Amarachi, AP Chinazom, E Adaeze… - Pharmacological …, 2022 - Elsevier
Alzheimer's disease (AD) is a progressive neurological disease and the most common form
of dementia, affecting more than 10 million people all over the world. Clinically, AD is …

Rutin improves anxiety and reserpine-induced depression in rats

AI Foudah, MH Alqarni, A Alam, S Devi, MA Salkini… - Molecules, 2022 - mdpi.com
Mental disorders have a poor clinical prognosis and account for approximately 8% of the
global burden of disease. Some examples of mental disorders are anxiety and depression …

Exploring the inhibition of quercetin on acetylcholinesterase by multispectroscopic and in silico approaches and evaluation of its neuroprotective effects on PC12 cells

Y Liao, X Mai, X Wu, X Hu, X Luo, G Zhang - Molecules, 2022 - mdpi.com
This study investigated the inhibitory mechanism of quercetin in acetylcholinesterase
(AChE) and its neuroprotective effects on β-amyloid25–35-induced oxidative stress injury in …

A nanoplatform-based aptasensor to electrochemically detect epinephrine produced by living cells

Z Fredj, P Wang, F Ullah, M Sawan - Microchimica Acta, 2023 - Springer
A novel aptasensor has been designed for quantitative monitoring of epinephrine (EP)
based on cerium metal–organic framework (CeMOF) loaded gold nanoparticles (AuNPs) …

[HTML][HTML] Parthenolide alleviates cognitive dysfunction and neurotoxicity via regulation of AMPK/GSK3β (Ser9)/Nrf2 signaling pathway

J Sun, L Li, L Xiong, F Chen, L She, H Tang… - Biomedicine & …, 2023 - Elsevier
Alzheimer's disease (AD) stands as the predominant age-related neurodegenerative
disorder, for which efficacious treatment remains elusive. An auspicious avenue for this …

[HTML][HTML] A frugal printed electrochemical architecture to monitor dopamine release in mice brain: Organ-on-screen-printed approach

M Verde, P Lippiello, S Singh, MC Miniaci… - … and Bioelectronics: X, 2022 - Elsevier
Dopamine (DA) is an important catecholamine neuromodulator that is present in the brain of
mammal, and changes of its level can be related to some neurological diseases such as …

Natural products in the management of neurodegenerative diseases

R Goyal, P Mittal, RK Gautam, MA Kamal… - Nutrition & …, 2024 - Springer
Neurodegenerative diseases represent one of the utmost imperative well-being health
issues and apprehensions due to their escalating incidence of mortality. Natural derivatives …

Identification of BACE-1 Inhibitors against Alzheimer's Disease through E-Pharmacophore-Based Virtual Screening and Molecular Dynamics Simulation Studies: An …

K Chidambaram - Life, 2023 - mdpi.com
Alzheimer is a severe memory and cognitive impairment neurodegenerative disease that is
the most common cause of dementia worldwide and characterized by the pathological …

New Hybrid Compounds Incorporating Natural Products as Multifunctional Agents against Alzheimer's Disease

L Ciccone, C Camodeca, N Tonali, L Barlettani… - Pharmaceutics, 2023 - mdpi.com
A series of new hybrid derivatives 1a–c, 2a–c, 3a–c, 4a–c, 5a–c, inspired by nature, were
synthesized and studied as multifunctional agents for the treatment of Alzheimer's disease …