Teratogenic effects of maternal drug abuse on developing brain and underlying neurotransmitter mechanisms

B Little, N Sud, Z Nobile, D Bhattacharya - Neurotoxicology, 2021 - Elsevier
The aim of this review is to highlight our knowledge of the various drugs of abuse that can
prove potential teratogens affecting the brain and cognitive development in an individual …

Acetylsalicylic acid suppresses alcoholism-induced cognitive impairment associated with atorvastatin intake by targeting cerebral miRNA155 and NLRP3: in vivo, and …

DI Mohamed, D Alaa El-Din Aly El-Waseef, ES Nabih… - Pharmaceutics, 2022 - mdpi.com
Alcoholism is one of the most common diseases that can lead to the development of several
chronic diseases including steatosis, and cognitive dysfunction. Statins are lipid-lowering …

Melatonin ameliorates methamphetamine-induced cognitive impairments by inhibiting neuroinflammation via suppression of the TLR4/MyD88/NFκB signaling …

T Lwin, JL Yang, S Ngampramuan, K Viwatpinyo… - Progress in Neuro …, 2021 - Elsevier
Methamphetamine (METH) is a highly addictive psychostimulant that causes significant
health issues due to high prevalence of its illegal use. Chronic use of METH is associated …

Effects of environmental enrichment on behavioral deficits and alterations in hippocampal BDNF induced by prenatal exposure to morphine in juvenile rats

A Ahmadalipour, J Sadeghzadeh, AA Vafaei… - Neuroscience, 2015 - Elsevier
Prenatal morphine exposure throughout pregnancy can induce a series of neurobehavioral
and neurochemical disturbances by affecting central nervous system development. This …

Co-treatment of vitamin D supplementation with enriched environment improves synaptic plasticity and spatial learning and memory in aged rats

M Bayat, KA Kohlmeier, M Haghani, AB Haghighi… - …, 2021 - Springer
Rationale and objective Environmental enrichment (EE) has been shown in old rats to
improve learning and memory. Vitamin D (VitD) has also been shown to modulate age …

Neurobehavioral effects of restricted and unpredictable environmental enrichment in rats

M Rojas-Carvajal, A Sequeira-Cordero… - Frontiers in …, 2020 - frontiersin.org
To study how motivational factors modulate experience-dependent neurobehavioral
plasticity, we modify a protocol of environmental enrichment (EE) in rats. We assumed that …

Early exposure to environmental enrichment modulates the effects of prenatal ethanol exposure upon opioid gene expression and adolescent ethanol intake

A Wille-Bille, F Bellia, AMJ García… - …, 2020 - Elsevier
Prenatal ethanol exposure (PEE) promotes ethanol consumption in the adolescent offspring
accompanied by the transcriptional regulation of kappa opioid receptor (KOR) system …

Sex‐specific effects of developmental morphine exposure and rearing environments on hippocampal spatial memory

A Sarkaki, SA Mard, N Bakhtiari… - International Journal of …, 2023 - Wiley Online Library
Developmental morphine (MOR) exposure (DME) detrimentally affects the cognitive abilities
of the next generation. It is shown that postnatal rearing environments and prenatal …

Environmental enrichment during adolescence mitigates cognitive deficits and alcohol vulnerability due to continuous and intermittent perinatal alcohol exposure in …

A Brancato, V Castelli, G Lavanco… - Frontiers in Behavioral …, 2020 - frontiersin.org
Perinatal alcohol exposure affects ontogenic neurodevelopment, causing physical and
functional long-term abnormalities with limited treatment options. This study investigated …

The influence of environmental enrichment on cardiovascular and behavioral responses to social stress

MC Normann, N McNeal, A Dagner, E Ihm… - Psychosomatic …, 2018 - journals.lww.com
Objective Stress is linked to negative cardiovascular consequences and increases in
depressive behaviors. Environmental enrichment (EE) involves exposure to novel items that …