Carbapenem resistance is a major and an on-going public health problem globally. It occurs
mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas …

Although the rapid spread of carbapenemase-producing Gram-negatives (CPGNs) is
providing the scientific community with a great deal of information about the molecular …

We investigated the mechanisms of resistance to carbapenems, aminoglycosides,
glycylcyclines, tetracyclines, and quinolones in 90 multiresistant clinical strains of …

The optimal treatment for multidrug-resistant A. baumannii nosocomial infections has not
been established. Carbapenems are the mainstay of treatment in susceptible isolates …

Acinetobacter baumannii is an opportunistic Gram-negative pathogen with increasing
relevance in a variety of hospital-acquired infections especially among intensive care unit …

Objective: To assess the relative strengths and weaknesses of carbapenems by considering
their microbiological, clinical, pharmacokinetics and pharmacokinetic/pharmacodynamic …

Ventilator-associated pneumonia caused by ESKAPE organisms:... : Current Opinion in
Pulmonary Medicine Ventilator-associated pneumonia caused by ESKAPE organisms: cause …

Los carbapenems son los antibióticos β-lactámicos dotados de mayor espectro, actividad y
resistencia a las β-lactamasas. Por sus cualidades son imprescindibles en el tratamiento …

The in vitro activity of doripenem against prevalent nonfermentative Gram-negative bacilli
and Aeromonas spp. was evaluated. The collection comprised 15 236 nonduplicate clinical …

Aims: The aim of this study was to evaluate the in vitro activity of doripenem (DOR) alone
and in combination with a variety of commonly used anti-Acinetobacter chemotherapeutic …