Hypertransfusion regimens for thalassemic patients revolutionized the management of
severe thalassemia; transforming a disease which previously led to early infant death into a …

β-thalassemia, a hereditary blood disorder caused by defective synthesis of hemoglobin β
globin chains, leads to ineffective erythropoiesis and chronic anemia that may require blood …

Background Patients with transfusion-dependent thalassemia (TDT) require lifelong blood
transfusions and iron chelation therapy. Thus, patients afflicted with TDT often have to …

La anemia representa una enfermedad con una elevada prevalencia que está ligada a
situaciones precarias que viven los infantes. Objetivos: determinar la frecuencia de la …

Introduction Acute transfusion reactions are adverse events occurring within 24 hrs of
transfusion and cause simple-to-severe complications. They may vary with the blood …

Thalassemia and sickle cell disease are the most prevalent hemoglobin disorders in the
populations of Dammam, Al-Qatif and Al-Ahsa regions in the Eastern Province of Saudi …

Background β-thalassemia major (β-TM) is a common inherited hemolytic type of anemia.
Repeated blood transfusions predispose β-TM patients toward peroxidative tissue injury …

Abstract β-thalassemia is one of the commonest monogenic disorders in India and Punjab is
significantly impacted with an estimated 4700 patients with thalassemia major. Like several …

Sickle cell disease (SCD) and beta thalassemia major (βTM) are multisystemic, genetically
inherited diseases. They are caused by mutations of hemoglobin, which ultimately cause …

Background: Regular blood transfusion in children with beta thalassemia major lead
toperoxidative tissue injury secondary to iron overload, increased oxidative stress and …