Bone degeneration associated with various diseases is increasing due to rapid aging,
sedentary lifestyles, and unhealthy diets. Living bone tissue has bioelectric properties critical …

Tissues like bone and cartilage are remodeled dynamically for their functional requirements
by signaling pathways. The signals are controlled by the cells and extracellular matrix and …

Electrical stimulation can facilitate wound healing with high efficiency and limited side
effects. However, current electrical stimulation devices have poor conformability with …

The discovery of piezoelectricity, endogenous electric fields and transmembrane potentials
in biological tissues raised the question whether or not electric fields play an important role …

Biomolecular piezoelectric materials are considered a strong candidate material for
biomedical applications due to their robust piezoelectricity, biocompatibility, and low …

Tissue engineering often rely on scaffolds for supporting cell differentiation and growth.
Novel paradigms for tissue engineering include the need of active or smart scaffolds in order …

Wearable and implantable electroceuticals (WIEs) for therapeutic electrostimulation (ES)
have become indispensable medical devices in modern healthcare. In addition to …

New advances in tissue engineering are being made through the application of different
types of electrical stimuli to influence cell proliferation and differentiation. Developments …

Endogenous direct-current electric fields (dcEFs) occur in vivo in the form of epithelial
transcellular potentials or neuronal field potentials, and a variety of cells respond to dcEFs in …

Background: Electrical stimulation is used to treat nonunions and to augment spinal fusions.
We studied the biochemical pathways that are activated in signal transduction when various …