Bacteria have developed a large array of motility mechanisms to exploit available resources
and environments. These mechanisms can be broadly classified into swimming in aqueous …

Actin plays many well-known roles in cells, and understanding any specific role is often
confounded by the overlap of multiple actin-based structures in space and time. Here, we …

Actin cytoskeleton dynamics play vital roles in most forms of intracellular trafficking by
promoting the biogenesis and transport of vesicular cargoes. Mounting evidence indicates …

The intrinsically disordered region (IDR) is a preserved signature of phytobacterial type III
effectors (T3Es). The T3E IDR is thought to mediate unfolding during translocation into the …

Obligately intracytosolic rickettsiae that cycle between arthropod and vertebrate hosts cause
human diseases with a spectrum of severity, primarily by targeting microvascular endothelial …

Membrane trafficking pathways play a prominent role in plant immunity. The endomembrane
transport system coordinates membrane-bound cellular organelles to ensure that …

Mounting evidence suggests a causal relationship between specific bacterial infections or
microbial compositions and the development of certain malignant neoplasms. In this study …

Dynamin-like guanylate binding proteins (GBPs) are gamma interferon (IFN-γ)-inducible
host defense proteins that can associate with cytosol-invading bacterial pathogens. Mouse …

Rickettsia species of the spotted fever group are arthropod-borne obligate intracellular
bacteria that can cause mild to severe human disease. These bacteria invade host cells …

Listeria monocytogenes causes listeriosis, a foodborne disease that poses serious risks to
fetuses, newborns and immunocompromised adults. This intracellular bacterial pathogen …