Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Mitochondrial dysfunction constitutes one of the hallmarks of aging and is characterized by
irregular mitochondrial morphology, insufficient ATP production, accumulation of …

Proximity labeling catalyzed by promiscuous enzymes, such as TurboID, have enabled the
proteomic analysis of subcellular regions difficult or impossible to access by conventional …

Cells use mitophagy to remove dysfunctional or excess mitochondria, frequently in response
to imposed stresses, such as hypoxia and nutrient deprivation. Mitochondrial cargo …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Macroautophagy/autophagy refers to the engulfment of cellular contents selected for
lysosomal degradation. The final step in autophagy is the fusion of autophagosome with the …

In the past years, we have learnt that tumors co-evolve with their microenvironment, and that
the active interaction between cancer cells and stromal cells plays a pivotal role in cancer …

The elimination of mitochondria via autophagy, termed mitophagy, is an evolutionarily
conserved mechanism for mitochondrial quality control and homeostasis. Mitophagy …

Mitochondria in the cell are the center for energy production, essential biomolecule
synthesis, and cell fate determination. Moreover, the mitochondrial functional versatility …

Mitochondria are highly dynamic organelles and important for a variety of cellular functions.
They constantly undergo fission and fusion events, referred to as mitochondrial dynamics …