Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …

The golden Syrian hamster (Mesocricetus auratus) has long been a valuable rodent model
of human diseases, especially infectious and metabolic diseases. Hamsters have also been …

Abstract Ethnopharmacological relevance Taraxacum mongolicum Hand.-Mazz. has been
used in lung cancer treatment in Chinese medicine. However, its specific mechanism of …

Organoids have been developed in the last decade as a new research tool to simulate
organ cell biology and disease. Compared to traditional 2D cell lines and animal models …

Esophageal cancer (EC) is the tenth most common cancer worldwide and has high
morbidity and mortality. Its main subtypes include esophageal squamous cell carcinoma and …

Esophageal adenocarcinoma (EAC) is a subtype of esophageal cancer with significant
morbidity and mortality rates worldwide. Despite advancements in tumor models, the …

Background Esophageal cancer (EC) is a highly malignant tumor of the digestive tract.
Circular RNAs (circRNAs) have been verified to play a regulatory role in the occurrence and …

The lack of suitable translational research models reflecting primary disease to explore
tumorigenesis and therapeutic strategies is a major obstacle in esophageal …

Objective To analyze and evaluate the role of the High-throughput Drug Sensitivity (HDS)
screening strategy in identifying highly sensitive drugs against esophageal squamous cell …

Despite advancing therapeutic treatments, cancer remains the leading cause of death
worldwide, with most of its patients developing drug resistance and recurrence after initial …