The volume of a typical Eschericia coli nucleoid is roughly 104 times smaller than the
volume of a freely coiling linear DNA molecule with the same length as the E. coli genome …

The unconstrained genomic DNA of bacteria forms a coil, whose volume exceeds 1000
times the volume of the cell. Since prokaryotes lack a membrane-bound nucleus, in sharp …

Archaeal chromatin proteins share molecular and functional similarities with both bacterial
and eukaryotic chromatin proteins. These proteins play an important role in functionally …

The macromolecules of the bacterial cell occupy 20–40% of the total cytosol volume, and
crowded environments have long been known to compact and stabilize DNA. Nevertheless …

Escherichia coli nucleoids were compacted by the inert polymer polyethylene glycol (PEG)
in the presence of the H-NS protein. The protein by itself appears to have little impact on the …

Compaction of DNA by nonbinding macromolecules such as uncharged flexible polymer
chains and negatively charged globular proteins is thought to have various applications in …

Genome packaging in prokaryotic cells is believed to be carried out by a combination of
DNA-binding proteins, crowding effects, and DNA supercoiling. Much is known about DNA …

In the present work, we revisit the effect of macromolecular crowding on the sizes of flexible
neutral polymer chains. Motivated by recent experimental measurements on crowding …

34. Luger, K., Mader, AW, Richmond, RK, Sargent, DF and Richmond, TJ (1997) Crystal
structure of the nucleosome core particle at 2.8 A resolution. Nature, 389, 251-260. 35 …

Compaction of DNA by nonbinding macromolecules such as uncharged flexible polymer
chains and negatively charged globular proteins is thought to have various applications in …