The evolution of synthetic receptor systems
Receptors enable cells to detect, process and respond to information about their
environments. Over the past two decades, synthetic biologists have repurposed physical …
environments. Over the past two decades, synthetic biologists have repurposed physical …
[HTML][HTML] Safety switches for adoptive cell therapy
AC Sahillioglu, TN Schumacher - Current opinion in immunology, 2022 - Elsevier
Highlights•Synthetic biology tools enable reversible and dose dependent control of cell
products.•Drug responsive switches modulate endogenous and transduced antigen receptor …
products.•Drug responsive switches modulate endogenous and transduced antigen receptor …
Synergies between therapeutic ultrasound, gene therapy and immunotherapy in cancer treatment
Due to the ease of use and excellent safety profile, ultrasound is a promising technique for
both diagnosis and site-specific therapy. Ultrasound-based techniques have been …
both diagnosis and site-specific therapy. Ultrasound-based techniques have been …
Externally-controlled systems for immunotherapy: from bench to bedside
M Tristán-Manzano, P Justicia-Lirio… - Frontiers in …, 2020 - frontiersin.org
Immunotherapy is a very promising therapeutic approach against cancer that is particularly
effective when combined with gene therapy. Immuno-gene therapy approaches have led to …
effective when combined with gene therapy. Immuno-gene therapy approaches have led to …
Mechanogenetics for cellular engineering and cancer immunotherapy
Recent synthetic biology advancements have shown that cells can be engineered to
respond to external stimuli such as chemical compounds and light, which significantly …
respond to external stimuli such as chemical compounds and light, which significantly …